1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8 Purity ≥99.0% Olaparib Intermediate Factory
Olaparib and Related Intermediates:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid CAS 763114-26-7
1-(Cyclopropylcarbonyl)piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
Chemical Name | 1-(Cyclopropylcarbonyl)piperazine Hydrochloride |
CAS Number | 1021298-67-8 |
CAT Number | RF-PI452 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C8H14N2O·HCl |
Molecular Weight | 190.67 |
Melting Point | 175.0 to 179.0℃ |
Solubility | Soluble in Water |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White Powder |
Purity | ≥99.0% |
Moisture (K.F) | ≤0.50% |
Single Impurity | ≤0.50% |
Total Impurities | ≤1.0% |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediate |
Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
1-(Cyclopropylcarbonyl)piperazine Hydrochloride (CAS: 1021298-67-8) is used as a pharmaceutical intermediate. It can be used as a intermediate of Olaparib (CAS: 763113-22-0). Olaparib is a potent inhibitor of both PARP-1 and PARP-2 and is strongly sensitive to KB2P cells due to suppression of base excision repair by PARP inhibition. Olaparib was approved in 2014 by FDA for treating advanced ovarian cancer.