1,4-Dibromobutane CAS 110-52-1 Purity >99.0% (GC) Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1,4-Dibromobutane (CAS: 110-52-1) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in 1,4-Dibromobutane, please send CAS number, quantity to us. Please contact: alvin@ruifuchem.com
Chemical Name | 1,4-Dibromobutane |
Synonyms | 1,4-Dibromo Butane; Tetramethylene Bromide; 1,4-Butylenedibromide; 1,4-Dibrombutan; Tetramethylene Dibromide; α,ω-Dibromobutane |
Stock Status | In Stock, Production Capacity 50 Tons per Month |
CAS Number | 110-52-1 |
Molecular Formula | C4H8Br2 |
Molecular Weight | 215.92 |
Melting Point | -20℃(lit.) |
Boiling Point | 194.0~196.0℃ at 760mmHg |
Flash Point | 131℃(267°F) |
Density | 1.808 g/mL at 25℃(lit.) |
Refractive Index n20/D | 1.519(lit.) |
Sensitive | Air Sensitive, Light Sensitive |
Water Solubility | Immiscible With Water |
Solubility | Soluble in Acetone, Ether, Chloroform, Ethanol |
Shipping Condition | Ambient Temperatures |
COA & MSDS | Available |
Sample | Available |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Colorless or Light Yellow Transparent Liquid (Eye-Measurement) |
Purity / Analysis Method | >99.0% (GC) |
Moisture (by K.F) | ≤0.05% |
PH Value | 6.0~8.0 (1:1 Water Solution) |
Refractive Index n20/D | 1.517~1.521 |
Total Impurities | <1.00% |
Infrared Spectrum | Conforms to Structure |
Test Standard | Enterprise Standard |
Main Usage |
Organic Synthesis Intermediates |
Package: Fluorinated Bottle, 25kg/Drum, 180kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from air, light and moisture.
Stability: Stable. Combustible.Incompatible With Strong Oxidizing Agents, Strong Bases.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes
R25 - Toxic if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39 - Wear suitable gloves and eye/face protection
UN IDs UN 2810 6.1/PG 3
WGK Germany 2
RTECS EJ7565000
TSCA Yes
Hazard Class 6.1(b)
Packing Group III
1,4-Dibromobutane (CAS: 110-52-1) is used as an intermediate involved in the synthesis of active pharmaceutical ingredient and other organic compounds. Organic synthesis intermediates. 1,4-Dibromobutane is used for the manufacture of aminophylline, kebiqing, expelling Qingjing, etc. 1,4-Dibromobutane is used as a catalyst in the polymerization of 2-oxazolines. Also used in the synthesis of cholinesterase inhibitors used against Alzheimer’s disease.
1. 1,4-Dibromobutane is derived from tetrahydrofuran by ring opening and bromination. Hydrobromic acid was added to the reaction Pan, tetrahydrofuran was added dropwise under stirring, and sulfuric acid was added dropwise, and the temperature was controlled to be below 50℃. After completion of the reaction, the mixture was stirred for 1H. The lower solution was separated by cooling, washed with soda ash solution until neutral, dried with anhydrous calcium chloride, and filtered to obtain the finished product.
2. Derived from the bromination of 1,4-Butanediol. Hydrobromic acid was added to the reaction pot, cooled to 10℃ with stirring, and sulfuric acid was added dropwise. After completion of the addition, 1,4-Butanediol was further added dropwise at a temperature not exceeding 15℃, and the mixture was stirred for half an hour. Incubation was performed for 6h at 100-110℃. Cool to room temperature, separate the lower liquid, wash with soda ash solution to neutral. After Dehydration of calcium chloride, 1,4-Dibromobutane was obtained by filtration.
Store in a cool and ventilated warehouse, away from the fire. Keep the container sealed and stored away from the oxidant. Emergency handling equipment and appropriate containment materials should be provided.