18 Years Factory Isovaleroyl Chloride - 2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory – Ruifu

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18 Years Factory Isovaleroyl Chloride - 2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory – Ruifu Detail:

Manufacturer Supply, High Purity, Commercial Production
Chemical Name: 2-Chloroadenine
CAS: 1839-18-5

Chemical Name	2-Chloroadenine
Synonyms	6-Amino-2-Chloropurine; Cladribine EP Impurity B
CAS Number	1839-18-5
CAT Number	RF-PI513
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C5H4ClN5
Molecular Weight	169.57
Brand	Ruifu Chemical

Item	Specifications
Appearance	Yellowish to Off-White Powder
Assay / Analysis Method	≥98.0% (HPLC)
Melting Point	≥300℃
Loss on Drying	≤0.50%
Residue on Ignition	≤0.50%
Heavy Metals (as Pb)	≤0.001%
Total Impurities	≤2.0%
Test Standard	Enterprise Standard
Usage	Intermediate of Clofarabine (CAS: 123318-82-1), Cladribine (CAS: 4291-63-8)

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

2-Chloroadenine (CAS: 1839-18-5) is mainly used as intermediate of Clofarabine (CAS: 123318-82-1), Cladribine (CAS: 4291-63-8) and other APIs. Clofarabine is a novel purine nucleoside anticancer drugs is first successfully developed by the Top10 biopharmaceutical company of the United States-Genzyme Corporation. On December 28, 2004 the US food and Drug Administration (FDA) used fast-track for approval of clofarabine for application to children with refractory or relapsed acute lymphocytic leukemia. Cladribine (2-chloro-2′-deoxyadenosine) is an adenosine deaminase-resistant analogue of deoxyadenosine. The drug has a broad range of in vitro activity against both lymphoid and myeloid neoplasms.

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