2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Purity >99.0% (HPLC) Tipiracil Hydrochloride Intermediate Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading supplier of 2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) with high quality, mainly used as an intermediate of Tipiracil Hydrochloride (CAS: 183204-72-0).
Ruifu Chemical has been supplying pharmaceutical intermediates more than 15 years.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase 2-Amino-1-Pyrroline Hydrochloride, please contact us by e-mail: alvin@ruifuchem.com
| Tipiracil Hydrochloride | CAS: 183204-72-0 |
| 6-(Chloromethyl)uracil | CAS: 18592-13-7 |
| 6-(Hydroxymethyl)uracil | CAS: 22126-44-9 |
| 2-Amino-1-Pyrroline Hydrochloride | CAS 7544-75-4 |
| Chemical Name | 2-Amino-1-Pyrroline Hydrochloride |
| Synonyms | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride; 2-Aminopyrrolidine HCl |
| CAS Number | 7544-75-4 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C4H8N2·HCl |
| Molecular Weight | 120.58 |
| Melting Point | 171.0 to 175.0℃ |
| Storage Conditions | Store Under Inert Gas (Nitrogen or Argon) at 2-8℃ |
| Sensitive | Hygroscopic |
| Shelf Life | 24 Months When Properly Stored |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories | Pharmaceutical Intermediates |
| Brand | Ruifu Chemical |
| Item | Specifications | Results |
| Appearance | White Powder | White Powder |
| Purity / Analysis Method | >99.0% (HPLC) | 99.8% |
| Melting Point | 171.0-175.0℃ | 172.0-174.0℃ |
| Largest Single Impurity | <0.50% | 0.09% |
| Water Content (K.F) | <0.50% | 0.45% |
| 1H NMR Spectrum | Conforms to Structure | Conforms |
| Test Standard | Enterprise Standard | Conforms |
| Application | Intermediate of Tipiracil Hydrochloride (CAS: 183204-72-0) | |
Package: Fluorinated bottle, aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store under inert gas (nitrogen or argon) at 2-8℃. Store in a cool, dry and well-ventilated warehouse away from incompatible substances. Prevent direct sunlight; avoid fire and heat sources; avoid water/moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
| UN IDs | UN 1993 3/PG III |
| Hazard Class | 3 |
| Packing Group | III |
2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) is a heterocyclic organic compound, which can be used as a pharmaceutical intermediate. 2-Amino-1-Pyrroline Hydrochloride is an intermediate of Tipiracil Hydrochloride (CAS: 183204-72-0) in the treatment of Rectal Cancer.
Tipiracil Hydrochloride is a potent and competitive inhibitor of thymidine phosphorylase (TPase) with an IC50 value of 35 nM for human placental TPase. It is selective for TPase over other pyrimidine-metabolizing enzymes (IC50s = >1 mM for UPase, OPRTase, TK, and DPDase). TPI inhibits the phosphorolysis and degradation of trifluorothymidine, a cytotoxic nucleoside, in human breast and colon carcinoma tumor samples. Oral administration of TPI (12.5-50 mg/kg) enhances the anti-tumor activity of trifluorothymidine in a mouse AZ-521 stomach cancer xenograft model. Formulations containing TPI have been used for the treatment of metastatic colorectal cancer.
