2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7 Purity ≥99.0% (HPLC) Trelagliptin Succinate Intermediate Factory

Short Description:

Chemical Name: 2-Cyano-5-Flurobenzyl Bromide

Synonyms: 2-(Bromomethyl)-4-Fluorobenzonitrile

CAS: 421552-12-7

Appearance: White to Off-Yellow Powder

Purity: ≥99.0% (HPLC) 

Intermediate of Trelagliptin Succinate (CAS: 1029877-94-8)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com


Product Detail

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Description:

Commercial Supply Trelagliptin Succinate Related Intermediates:
6-Chloro-3-Methyluracil CAS 4318-56-3
2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Intermediate-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 2-Cyano-5-Flurobenzyl Bromide
Synonyms 2-(Bromomethyl)-4-Fluorobenzonitrile
CAS Number 421552-12-7
CAT Number RF-PI143
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H5BrFN
Molecular Weight 214.03
Melting Point 67.0 to 71.0℃
Sensitive Moisture Sensitive
Solubility  Soluble in Methanol
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-Yellow Powder 
Purity / Analysis Method ≥99.0% (HPLC) 
Moisture (K.F) ≤0.50%
Residue on Ignition ≤0.30%
Single Impurity ≤0.50%
Total Impurities ≤1.00%
1 H NMR Spectrum Consistent With Structure
Test Standard Enterprise Standard
Usage Trelagliptin Succinate (CAS: 1029877-94-8) Intermediate 

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

1

FAQ:

2

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 2-Cyano-5-Flurobenzyl Bromide (CAS: 421552-12-7) with high quality, widely used in organic synthesis, synthesis of pharmaceutical intermediates and active pharmaceutical ingredient (API) synthesis. 2-Cyano-5-Flurobenzyl Bromide can be used in the synthesis of Trelagliptin Succinate (CAS: 1029877-94-8). Trelagliptin Succinate is a selective, long acting dipeptidyl peptidase-4 (DPP-4) inhibitor. An antidiabetic agent. Orally active DPP-4 inhibitor that produces clinically and statistically significant improvements in glycaemic control in patients with type 2 diabetes. Trelagliptin Succinate was approved for use in Japan in March 2015.

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