2-Mercapto-5-Methoxybenzimidazole CAS 37052-78-1 Purity ≥99.5% (HPLC) Omeprazole and Esomeprazole Intermediate Factory

Short Description:

Chemical Name: 2-Mercapto-5-Methoxybenzimidazole 

CAS: 37052-78-1

Purity: ≥99.5% (HPLC)

Appearance: White to Off-White Crystalline Powder

Intermediate of Omeprazole (CAS: 73590-58-6) and Esomeprazole (CAS: 119141-88-7)

Contact: Dr. Alvin Huang 

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Omeprazole Intermediates:

37052-78-1 - Chemical Properties:

Chemical Name 2-Mercapto-5-Methoxybenzimidazole
Synonyms 5-Methoxye-2-Mercaplobenzinidazole; 5-Methoxy-2-Benzimidazolethiol 
CAS Number 37052-78-1
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H8N2OS
Molecular Weight 180.23 
Solubility  Insoluble in Water
Sensitive Air Sensitive 
COA & MSDS Available
Origin Shanghai, China
Category   Pharmaceutical Intermediates
Brand Ruifu Chemical

37052-78-1 - Specifications:

Item Specifications
Appearance White to Off-White Crystalline Powder
Purity / Analysis Method ≥99.5% (HPLC)  
Identification IR Absorption: Conforms to Standard
Melting Point 255.0~259.0℃
Water (K.F) ≤0.50%
Residue on Ignition ≤0.20%
Single Max. Impurity ≤0.50% (HPLC)  
Total Impurities ≤0.50% (HPLC)  
Test Standard Enterprise Standard
Usage Intermediate of Omeprazole (CAS: 73590-58-6) and Esomeprazole (CAS: 119141-88-7)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

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37052-78-1 - Application:

2-Mercapto-5-Methoxybenzimidazole (CAS: 37052-78-1), it acts as a pharmaceutical intermediate for manufacture of Omeprazole (CAS: 73590-58-6) and Esomeprazole (CAS: 119141-88-7). Omeprazole was introduced in the 1980s. Omeprazole is a proton pump inhibitor used to treat diseases like gastroesophageal reflux disease (GERD), used for gastric and duodenal ulcers, reflux or erosive esophagitis, and Zollinger-Ellison syndrome. It is also effective for gastric and duodenal ulcers that are ineffective with H2 receptor antagonists. Esomeprazole, is the S-isomer of omeprazole. In 1990, in vitro gastric gland model confirmed that two isomers of omeprazole have the same proton pump inhibitory effect.

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