2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu
2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu Detail:
Manufacturer with High Purity and Stable Quality
Supply Irinotecan and Related Intermediates:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Chemical Name | 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride |
CAS Number | 143254-82-4 |
CAT Number | RF-PI243 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C11H20Cl2N2O |
Molecular Weight | 267.2 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White or Light Yellow Powder |
Assay | ≥98.0% (HPLC) |
Loss on Drying | ≤1.0% |
Heavy Metals | ≤20ppm |
Test Standard | Enterprise Standard |
Usage | Intermediate of Irinotecan Hydrochloride (CAS: 100286-90-6) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride (CAS: 143254-82-4) with high quality. It is an intermediate typically in the synthesis of Irinotecan Hydrochloride (CAS: 100286-90-6), a DNA Topoisomerase I Inhibitor.
lrinotecan hydrochloride, a semi-synthetic, water soluble derivative of the potent anticancer agent camptothecin, was launched in Japan for the treatment of lung, ovarian, and cervical cancers. lrinotecan exerts its antitumor activity via inhibition of topoisomerase I, a cellular enzyme that is involved in maintaining the topographic structure of DNA during the process of translation, transcription, and mitosis. lrinotecan undergoes de-esterification in vivo to yield an active metabolite, SN-38, which is 1000-fold more potent than the parent. Although being much less toxic than camptothecin, a significant number of patients in clinical trials exhibited side effects of leukopenia, diarrhea, nauseahromiting, and alopecia. Combination therapy of irinotecan with another widely used anticancer agent, cisplatin, has been reported to be superior to either agent alone. lrinotecan is in clinical trials for gastrointestinal, breast, skin, colorectal, pancreatic cancers, mesothelioma and non-Hodgkin’s lymphoma.
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We are experienced manufacturer. Wining the majority from the crucial certifications of its market for 2021 Good Quality Aminomalonic Acid Diethyl Ester Hydrochloride - 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity – Ruifu , The product will supply to all over the world, such as: Albania, Belgium, Sacramento, They are sturdy modeling and promoting effectively all over the world. Never ever disappearing major functions within a quick time, it's a have to in your case of fantastic good quality. Guided by the principle of "Prudence, Efficiency, Union and Innovation. the corporation. ake an excellent efforts to expand its international trade, raise its organization. rofit and raise its export scale. We have been confident that we've been going to have a bright prospect and to be distributed all over the world in the years to come.
By Maggie from Peru - 2018.04.25 16:46
The goods we received and the sample sales staff display to us have the same quality, it is really a creditable manufacturer.
By mary rash from South Korea - 2017.08.21 14:13