2021 Good Quality Methyl 5-bromo-6-chloropyridine-3-carboxylate - 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Purity ≥99.0% Sorafenib Tosylate Intermediate – Ruifu

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2021 Good Quality Methyl 5-bromo-6-chloropyridine-3-carboxylate - 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Purity ≥99.0% Sorafenib Tosylate Intermediate – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6

Name 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate
Synonyms Isocyanic Acid 4-Chloro-3-(Trifluoromethyl)phenyl Ester
CAS Number 327-78-6
CAT Number RF-PI167
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H3ClF3NO
Molecular Weight 221.56
Brand Ruifu Chemical
Item Specifications
Appearance White Crystalline
Purity / Analysis Method ≥99.0% (HPLC)
Identification (1) IR  (2) HPLC
Moisture (K.F) ≤0.50%
Heavy Metals ≤10ppm
Impurity A ≤0.15%
Impurity B ≤1.0%
Impurity C ≤1.0%
Other Single Impurity ≤0.50%
Total Impurities ≤2.0%
Test Standard Enterprise Standard
Usage Intermediate of Sorafenib Tosylate (CAS: 475207-59-1)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6

Sorafenib Tosylate (CAS: 475207-59-1) is a new type of multi-target antitumor drug, was developed by the German Bayer Pharmaceuticals, and displayed expansive antitumor activity in preclinical animal tests. Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and HCC. Sorafenib Tosylate (CAS: 475207-59-1) can simultaneously affect tumor cells and tumor blood vessels. It has a double antitumor effect: it can block the cell signal transduction pathways mediated by RAF/MEK/ERK to directly inhibit tumor cell growth, while also inhibiting VEGF and platelet derived growth factors (PDGF) receptors to prevent the formation of new tumor blood vessels, thus indirectly inhibiting tumor cell growth. Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.


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2021 Good Quality Methyl 5-bromo-6-chloropyridine-3-carboxylate - 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Purity ≥99.0% Sorafenib Tosylate Intermediate – Ruifu detail pictures


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Our staff are usually in the spirit of "continuous improvement and excellence", and while using the top-quality high-quality items, favorable value and superior after-sales services, we try to acquire each and every customer's belief for 2021 Good Quality Methyl 5-bromo-6-chloropyridine-3-carboxylate - 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Purity ≥99.0% Sorafenib Tosylate Intermediate – Ruifu , The product will supply to all over the world, such as: French, Auckland, New Delhi, The quality of our products is equal to OEM's quality, because our core parts are the same with OEM supplier. The above products have passed professional certification, and we not only can produce OEM-standard products but we also accept Customized Products order.
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