2021 Good Quality Methyl 5-bromo-6-chloropyridine-3-carboxylate - 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Purity ≥99.0% Sorafenib Tosylate Intermediate – Ruifu
2021 Good Quality Methyl 5-bromo-6-chloropyridine-3-carboxylate - 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Purity ≥99.0% Sorafenib Tosylate Intermediate – Ruifu Detail:
Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
Name | 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate |
Synonyms | Isocyanic Acid 4-Chloro-3-(Trifluoromethyl)phenyl Ester |
CAS Number | 327-78-6 |
CAT Number | RF-PI167 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C8H3ClF3NO |
Molecular Weight | 221.56 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White Crystalline |
Purity / Analysis Method | ≥99.0% (HPLC) |
Identification | (1) IR (2) HPLC |
Moisture (K.F) | ≤0.50% |
Heavy Metals | ≤10ppm |
Impurity A | ≤0.15% |
Impurity B | ≤1.0% |
Impurity C | ≤1.0% |
Other Single Impurity | ≤0.50% |
Total Impurities | ≤2.0% |
Test Standard | Enterprise Standard |
Usage | Intermediate of Sorafenib Tosylate (CAS: 475207-59-1) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
Sorafenib Tosylate (CAS: 475207-59-1) is a new type of multi-target antitumor drug, was developed by the German Bayer Pharmaceuticals, and displayed expansive antitumor activity in preclinical animal tests. Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and HCC. Sorafenib Tosylate (CAS: 475207-59-1) can simultaneously affect tumor cells and tumor blood vessels. It has a double antitumor effect: it can block the cell signal transduction pathways mediated by RAF/MEK/ERK to directly inhibit tumor cell growth, while also inhibiting VEGF and platelet derived growth factors (PDGF) receptors to prevent the formation of new tumor blood vessels, thus indirectly inhibiting tumor cell growth. Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.
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Like a result of ours specialty and repair consciousness, our enterprise has won a superb popularity amid buyers everywhere in the environment for 2021 Good Quality Methyl 5-bromo-6-chloropyridine-3-carboxylate - 4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS 327-78-6 Purity ≥99.0% Sorafenib Tosylate Intermediate – Ruifu , The product will supply to all over the world, such as: Liverpool, Iraq, Ghana, Our company offers the full range from pre-sales to after-sales service, from product development to audit the use of maintenance, based on strong technical strength, superior product performance, reasonable prices and perfect service, we will continue to develop, to provide the high-quality products and services, and promote lasting cooperation with our customers, common development and create a better future.
By Giselle from belarus - 2018.09.23 17:37
The customer service reprersentative explained very detailed, service attitude is very good, reply is very timely and comprehensive, a happy communication! We hope to have a opportunity to cooperate.
By Esther from Hongkong - 2017.08.15 12:36