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2021 New Style (S)-(+)-4-Phenyl-2-oxazolidinone - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu Featured Image
  • 2021 New Style (S)-(+)-4-Phenyl-2-oxazolidinone - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu

2021 New Style (S)-(+)-4-Phenyl-2-oxazolidinone - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu

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2021 New Style (S)-(+)-4-Phenyl-2-oxazolidinone - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Supply Irinotecan and Related Intermediates:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4

Chemical Name 7-Ethyl-10-Hydroxycamptothecin
Synonyms SN-38
CAS Number 86639-52-3
CAT Number RF-PI242
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C22H20N2O5
Molecular Weight 392.41
Brand Ruifu Chemical
Item Specifications
Appearance Light Yellowish White Crystals Powder
Identification (IR, UV) (1) Ultraviolet ray absorption spectrum accord with the demands
(2) Infrared ray absorption spectrum concordant with reference standard spectrum shall comply with approved tests
Melting Point 228.0~235.0℃
Related Substances ≤1.5%
10-Hydroxycamptothecin ≤0.30%
7-Cthylcamptothecin ≤0.70%
Maximum Unknown Impurity ≤0.50%
Loss on Drying ≤1.0%
Heavy Metals ≤10ppm
Residue on Ignition ≤0.10%
Clarity of Solution Clear
Assay ≥98.0% (HPLC)
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediate of Irinotecan

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) with high quality. 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. 7-Ethyl-10-Hydroxycamptothecin (SN-38), is the active metabolite of Irinotecan, a semisynthetic derivative of camptothecin, a quinoline-based alkaloid found in the bark of the Chinese camptotheca tree and the Asian nothapodytes tree. Although 7-Ethyl-10-Hydroxycamptothecin is up to 1,000 times more potent than Irinotecan, it has not been converted into a viable drug candidate because it is insoluble. It is presently being subjected to clinical trials in combination with other moieties which may ultimately allow it to be efficacious as an antineoplastic drug.

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2021 New Style (S)-(+)-4-Phenyl-2-oxazolidinone - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu detail pictures

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