2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Intermediate COVID-19

Short Description:

Name: 2,3,5-Tri-O-benzyl-D-ribonolactone

Synonyms: 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone

CAS: 55094-52-5

Appearance: White to Almost White Powder

Purity: ≥99.0%

Intermediate of Remdesivir (CAS 1809249-37-3) COVID-19

High Quality, Commercial Production

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Product Detail

Product Tags

Description:

Manufacturer Commercial Supply Remdesivir and Related Intermediates with High Quality
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
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2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Intermediate CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Chemical Properties:

Chemical Name	2,3,5-Tri-O-benzyl-D-ribonolactone
Synonyms	2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone; Remdesivir Intermediate
CAS Number	55094-52-5
CAT Number	RF-PI301
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C26H26O5
Molecular Weight	418.49
Melting Point	54.0-55.0℃
Storage Condition	Room Temperature
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Yellowish or White Solid
Solubility	Soluble in CH2Cl2 and Insoluble in H2O
NMR and MS	Should Comply
Identification	IR and TLC
Moisture	≤1.0%
Residue on Ignition	≤0.50%
Any Individual Impurity	≤0.50%
Heavy Metals	≤50ppm
HPLC (210nm)	≥99.0%
HPLC (ELSD)	≥99.0%
Test Standard	Enterprise Standard
Usage	Intermediate of Remdesivir (CAS 1809249-37-3)

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) is a Remdesivir intermediate. Remdesivir (CAS 1809249-37-3) is a novel antiviral drug in the class of nucleotide analogs, used in treatment of COVID-19. Remdesivir (GS-5734) is a novel antiviral nucleoside analogue that inhibits murine hepatitis virus (MHV) with similar EC50 as SARS-CoV and MERS-CoV. Coronaviruses (CoVs) are positive-sense, single-stranded RNA viruses that infect a wide range of animal hosts. In humans, CoVs were recognized as typically causing colds and pneumonia until the emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 from zoonotic sources. Remdesivir is the monophosphoramidate prodrug of the C-adenosine nucleoside analogue GS-441524. In delayed brain tumor (DBT) cells infected with MHV, GS-5734 inhibited MHV more potently than GS-441524, with a GS-5734 EC50 of 0.03 M. Furthermore, EC50 values were determined after treatment with GS-441524 and GS-5734 in SARS-CoV- and MERS-CoV-infected primary human airway epithelial cell (HAE) cultures.