3-Ethoxy-4-Methoxybenzaldehyde CAS 1131-52-8 Purity >98.0% (HPLC) Apremilast Intermediate

Short Description:

Chemical Name: 3-Ethoxy-4-Methoxybenzaldehyde 

CAS: 1131-52-8

Purity: >98.0% (HPLC)

Appearance: White to Tan Powder or Chunks

Intermediate / Impurity of Apremilast (CAS: 608141-41-9)  

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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1131-52-8 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 3-Ethoxy-4-Methoxybenzaldehyde (CAS: 1131-52-8) with high quality, intermediate of Apremilast (CAS: 608141-41-9). Apremilast is used for the treatment of active psoriatic arthritis (PsA) and moderate to severe chronic plaque psoriasis (PSOR).
Ruifu Chemical can provide high-quality Apremilast intermediates and impurities.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Apremilast intermediates and impurities or other products, please e-mail: alvin@ruifuchem.com

Intermediates of Apremilast:

1131-52-8 - Chemical Properties:

Chemical Name 3-Ethoxy-4-Methoxybenzaldehyde 
Synonyms 3-Ethoxy-p-Anisaldehyde; Apremilast Impurity
Stock Status In Stock, Commercial Production  
CAS Number 1131-52-8
Molecular Formula C10H12O3
Molecular Weight 180.20 g/mol
Melting Point 51.0~53.0℃ 
Boiling Point 155℃/10 mmHg 
Flash Point >113℃(235.4°F)
Density 1.088±0.06 g/cm3 
Refractive Index n20/D 1.536
Store Under Inert Gas Store Under Inert Gas
Sensitive Air Sensitive  
Solubility  Soluble in Methanol
Storage Temperature Store Long-Term in a Cool and Dry Place 
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
Pharmaceutical Intermediate; Apremilast Intermediate 
Brand Ruifu Chemical

1131-52-8 - Specifications:

Items Specifications  Results
Appearance White to Tan Powder or Chunks   Conforms  
Melting Point 51.0~53.0℃ 51.0~52.0℃
Loss on Drying <1.00% 0.23%
Purity / Analysis Method >98.0% (HPLC)  98.5%
1H NMR Spectrum Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications

1131-52-8 - Package/Storage/Shipping:

Package: Fluorinated bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Air sensitive. Keep the container tightly closed. Store in a cool, dry, well-ventilated warehouse. Keep away from sunshine; avoid fire and heat sources; avoid moisture. Store away from oxidizing agents, air.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

1131-52-8 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

1131-52-8 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

1131-52-8 - Risk and Safety:

Hazard Symbols Xi - Irritant
Safety Description S23 - Do not breathe vapour.
S24/25 - Avoid contact with skin and eyes.
WGK Germany 3
HS Code 2912499090
Hazard Class IRRITANT

1131-52-8 - Application:

3-Ethoxy-4-Methoxybenzaldehyde (CAS: 1131-52-8) is used as a pharmaceutical intermediate, intermediate / impurity of Apremilast (CAS: 608141-41-9). Apremilast is a phosphodiesterase 4 (PDE4) inhibitor that works to suppress the immune system, which reduces inflammation. Apremilast is used to treat active psoriatic arthritis in adults. Apremilast is also used to treat moderate to severe plaque psoriasis in adults who may also receive phototherapy or other treatments for psoriasis.

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