3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9 Olaparib Intermediate Factory
Ruifu Chemical is the leading manufacturer of 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid (CAS: 61260-15-9) with high quality, intermediate of Olaparib (CAS: 763113-22-0), PARP-Inhibitor. Ruifu Chemical has been supplying pharmaceutical intermediates and active pharmaceutical ingredients (APIs), fine chemicals more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service. Purchase our products, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid |
| Synonyms | Dimethyl 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonate; 3-Dimethoxyphosphoryl-3H-2-Benzofuran-1-one |
| CAS Number | 61260-15-9 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C10H11O5P |
| Molecular Weight | 242.17 |
| Melting Point | 97.0~99.0℃ |
| Density | 1.35 |
| Storage Condition | Store Under Inert Gas (Nitrogen or Argon) at 2~8℃ |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories | Pharmaceutical Intermediates |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White or Almost White Powder |
| Purity | ≥98.0% |
| Moisture (K.F) | ≤0.50% |
| Total Impurities | ≤2.00% |
| Infrared Spectrum | Conforms to Structure |
| NMR Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Olaparib (CAS: 763113-22-0) PARP-Inhibitor |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse. Keep away from sunshine; avoid fire and heat sources; avoid moisture. Keep away from strong oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid (CAS: 61260-15-9), intermediate of Olaparib (CAS: 763113-22-0). Olaparib is a kind of novel poly ADP-ribose polymerase (PARP) inhibitors, including PARP1, PARP2, and PARP3. PARP mediates a DNA-repair mechanism which plays a important role in DNA damage repair and apoptosis, so olaparib specifically targets on the DNA repair mechanism of the targeting cell DNA repair and take effects by attacking the critical vulnerabilities of cancer cells carrying mutations in BRCA1 and BRCA2. Owing to this mechanism, it can be used for the maintenance therapy of patients of severe recurrent ovarian cancer who has breast cancer susceptibility gene (BRCA) mutation as well as being sensitive to platinum drug.
