4-Amino-2-Methylbenzoic Acid CAS 2486-75-1 Tolvaptan Intermediate Factory
Manufacturer Supply, High Quality, Commercial Production
Tolvaptan and Related Intermediates:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Chemical Name | 4-Amino-2-Methylbenzoic Acid |
| Synonyms | 4-Amino-o-toluic Acid; Tolvaptan Intermediate N-2 |
| CAS Number | 2486-75-1 |
| CAT Number | RF-PI394 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.17 |
| Solubility | Soluble in Methanol |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White or Yellowish Crystal Powder |
| Purity/Analysis Method | ≥99.0% (HPLC) |
| Moisture | ≤0.50% (K.F) |
| Melting Point | 161.0~168.0℃ |
| Residue on Ignition | ≤0.50% |
| Single Impurity | ≤0.50% |
| Total Impurities | ≤1.0% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Tolvaptan (CAS 150683-30-0), treatment of Hyponatremia |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
4-Amino-2-Methylbenzoic Acid (CAS 2486-75-1) is used as an intermediate in the synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API) synthesis. 4-Amino-2-Methylbenzoic Acid is the intermediate of Tolvaptan (CAS 150683-30-0). Tolvaptan is an oral selective vasopressin antagonist developed by Otsuka for the treatment of hyponatremia, and it is a non-peptide selective antidiuretic hormone receptor antagonist. The drug can increase the concentration of sodium ions in the plasma, and help the excess water discharge from the urine. The drug could enhance the ability of the kidney to deal with water, and significantly reduce the weight and edema of patients while not accompanied by increased electrolyte excretion, without destroying the blood electrolyte balance. The drug can be used to treat hyponatremia caused by congestive heart failure, various edematous diseases, cirrhosis and antidiuretic hormone deficiency syndrome.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchem.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
