4-Amino-3,5-Dichloropyridine CAS 22889-78-7 Roflumilast Interemdiate Purity ≥99.5%
Ruifu Chemical Supply Roflumilast Intermediates:
Roflumilast CAS 162401-32-3
4-Amino-3,5-Dichloropyridine CAS 22889-78-7
Chemical Name | 4-Amino-3,5-Dichloropyridine |
Synonyms | 3,5-Dichloro-4-Pyridinamine; Roflumilast Impurity C |
CAS Number | 22889-78-7 |
CAT Number | RF-PI647 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C5H4Cl2N2 |
Molecular Weight | 163.00 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White Crystalline Powder |
Purity / Analysis Method | ≥99.5% (HPLC) |
Melting Point | 158.0~162.0℃ |
Moisture (K.F) | ≤0.50% |
Ash Content | ≤0.50% |
Total Impurities | ≤0.50% |
Test Standard | Enterprise Standard |
Usage | Interemdiate of Roflumilast (CAS: 162401-32-3) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
4-Amino-3,5-Dichloropyridine (CAS: 22889-78-7) is the interemdiate of Roflumilast (CAS: 162401-32-3). Roflumilast is a selective oral phosphodiesterase-4 (PDE-4) inhibitor and a benzamide compound. It was developed by the German company Altana in 1993 and is the only oral PDE-4 inhibitor used to treat respiratory tract diseases approved for sale. Roflumilast is the first drug of its kind to target severe chronic obstructive pulmonary disease (COPD), and it is also the first oral anti-inflammation drug specifically developed for COPD patients.