5-Acetyl-3-Chloroiminodibenzyl CAS 25961-11-9 Clomipramine Hydrochloride Intermediate Purity >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 5-Acetyl-3-Chloroiminodibenzyl (CAS: 25961-11-9) with high quality, an intermediate for the synthesis of Clomipramine Hydrochloride. Ruifu can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase 5-Acetyl-3-Chloroiminodibenzyl, Please contact: alvin@ruifuchem.com
| Chemical Name | 5-Acetyl-3-Chloroiminodibenzyl |
| Synonyms | 3-Chloro-5-Acetyliminodibenzyl; 5-Acetyl-3-Chloro-10,11-Dihydrodibenzo[b,f]azepine; 5-Acetyl-3-Chloro-10,11-Dihydro-5H-Dibenz[b,f]azepine; 5-Acetyl-3-Chloro-2,2'-Iminodibenzyl; 1-(3-Chloro-10,11-Dihydro-5H-Dibenzo[b,f]azepin-5-yl)ethanone |
| Stock Status | In Stock, Commercially Manufactured |
| CAS Number | 25961-11-9 |
| Molecular Formula | C16H14ClNO |
| Molecular Weight | 271.74 g/mol |
| Melting Point | 120.0 to 125.0℃ |
| Density | 1.246±0.06 g/cm3 |
| Solubility | Soluble in Methanol |
| Storage Temp. | Cool & Dry Place |
| COA & MSDS | Available |
| Category | Intermediate of Clomipramine Hydrochloride |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | Light Yellow or Almost White Crystalline Powder (Visual) | Complies |
| Melting Point | 120.0 to 125.0℃ | 121.0~122.0℃ |
| Loss on Drying | <0.50% | 0.31% |
| 3,7-Dichloro-5-Acetyl Iminodibenzyl | <0.50% (HPLC) | Complies |
| 3-Amino-5-Acetyl Iminodibenzyl | <0.50% (HPLC) | Complies |
| Total Impurities | <1.00% (HPLC) | Complies |
| Purity / Analysis Method | >99.0% (HPLC) | 99.3% |
| 1 H NMR Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in a tightly closed container. Store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
5-Acetyl-3-Chloroiminodibenzyl (CAS: 25961-11-9) is used as an intermediate for the synthesis of Clomipramine Hydrochloride (CAS: 17321-77-6). Clomipramine is a tricyclic antidepressant, the 3-chlorinated derivative of imipramine . Like imipramine, clomipramine potently inhibits serotonin and norepinephrine reuptake (Kis = 7.4 and 96 nM, respectively). It also is an antagonist at histamine, muscarinic acetylcholine, α1-adrenergic, and dopamine receptors (Kds = 31, 37, 38, and 190 nM for H1, M1, α1, and D2, respectively). Clomidamine Hydrochloride Tablets (Anafenib) is a tricyclic antidepressant, the main function is to block the central nervous system The reuptake of norepinephrine and serotonin has a stronger blocking effect on the reuptake of serotonin, and it has antidepressant and anti-anxiety effects, as well as sedative and anticholinergic effects. The main effect is to block the reuptake of norepinephrine and serotonin in the central nervous system, and has a stronger blocking effect on the reuptake of serotonin. It has antidepressant and anxiolytic effects, as well as sedative and anticholinergic effects.
