5-Cyanoindole CAS 15861-24-2 Purity >99.0% (HPLC) Factory
Manufacturer Supply Related Intermediates
5-Cyanoindole CAS 15861-24-2
3-(4-Chlorobutyl)-5-Cyanoindole CAS 143612-79-7
Ethyl 5-Nitrobenzofuran-2-Carboxylate CAS 69604-00-8
Ethyl 5-Aminobenzofuran-2-Carboxylate CAS 174775-48-5
5-(Piperazin-1-yl)benzofuran-2-Carboxamide CAS 183288-46-2
CAS 163521-08-2
Chemical Name | 5-Cyanoindole |
Synonyms | 5-Cyano-1H-Indole; Indoline-5-Carbonitrile; 1H-Indole-5-Carbonitrile |
CAS Number | 15861-24-2 |
CAT Number | RF-PI1493 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C9H6N2 |
Molecular Weight | 142.16 |
Melting Point | 106.0~108.0℃ (lit.) |
Solubility | Soluble in Chloroform, Hexane and Methanol. Insoluble in Water |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Pale Yellow Crystalline Powder |
Identification | The retention time of the major peak in the chromatogram of the sample corresponds to that in the chromatogram obtained with the standard |
Purity / Analysis Method | >99.0% (HPLC) |
Loss on Drying | ≤0.20%(At 105°C for 3.0 hrs.) |
Water Content | ≤0.20% |
Residue on Ignition | ≤0.20% |
Single Impurity | ≤0.50% |
Total Impurities | <1.00% |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediates; Intermediate of API (CAS: 163521-08-2) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
5-Cyanoindole (CAS: 15861-24-2) is mainly used in pharmaceutical industry as a pharmaceutical intermediate. 5-Cyanoindole can be used as an intermediate of API (CAS: 163521-08-2), which is a kind of serotonergic antidepressant developed by Merck KGaA Company. API (CAS: 163521-08-2) is a novel compound with high affinity and selectivity for the 5-hydroxytrptamine (5-HT) transporter and 5-HT (1A) receptors, it is indicated for the treatment of major depressive disorder (MDD), it is can be used as an alternative drugs for other kind of antidepressant classes drugs that can’t be tolerated by patients. As a selective serotonin reuptake inhibitor, (CAS: 163521-08-2) can prevent the serotonin from re-entering into cell bodies, therefore making it remain longer inside the synapse. Moreover, (CAS: 163521-08-2) has a high selectivity for the serotonin-1A receptor, taking effect as a partial agonist that can simulate the production of serotonin. These effects result in increased serotonin in the synaptic cleft. This effect is related to the antidepressant effect of it in vivo.