6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9 PF-07321332 Boceprevir Intermediate
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6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9
Chemical Name | 6,6-Dimethyl-3-azabicyclo[3.1.0]hexane |
CAS Number | 943516-54-9 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C7H13N |
Molecular Weight | 111.18 |
Boiling Point | 135℃ |
Density | 0.911 |
COA & MSDS | Available |
Origin of Product | Shanghai, China |
Product Categories | Pharmaceutical Intermediates |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Colorless Transparent Liquid |
Purity | ≥98.0% (GC) |
Total Impurities | ≤2.00% |
Heavy Metals | ≤20ppm |
NMR Spectrum 1H | Conforms to Structure |
Test Standard | Enterprise Standard |
Usage: Intermediate of PF-07321332 Paxlovid (CAS 2628280-40-8) and Boceprevir (CAS 394730-60-0) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.
6,6-Dimethyl-3-azabicyclo[3.1.0]hexane (CAS 943516-54-9) is the intermediate of PF-07321332 Paxlovid (CAS 2628280-40-8) and Boceprevir (CAS 394730-60-0). Pfizer's Paxlovid PF-07321332 is an oral antiviral therapeutic targeting the SARS-CoV-2 betacoronavirus to prevent COVID-19. Paxlovid is a protease inhibitor that has demonstrated potent in vitro antiviral activity against SARS-CoV-2 and other coronaviruses, suggesting potential for use in the treatment of COVID-19, as well as potential use against future virus threats, says Pfizer. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay. Boceprevir inhibits SARS-CoV-2 3CLpro activity.