8 Year Exporter ECPPA - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu

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Our mission is usually to turn into an innovative provider of high-tech digital and communication devices by furnishing benefit added design and style, world-class manufacturing, and service capabilities for Molecular Weight 123.581, Formula Weight 255.35, Indacaterol Maleate CAS 753498-25-8), Our products are widely used in many industrial fields. Our Company Services Division in good faith for the purpose of the quality of survival. All for customer service.

8 Year Exporter ECPPA - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu Detail:

Manufacturer Supply; High Purity and Competitive Price
Shanghai Ruifu Chemical Co., Ltd. Commercial Supply Carfilzomib (CAS: 868540-17-4) Related Intermediates:
Boc-L-Leucine.H2O;Boc-L-Leucine monohydrate; CAS: 13139-15-6
Boc-L-Homophenylalanine; Boc-L-HomePhe-OH; CAS: 100564-78-1
2-Bromopropene CAS: 557-93-7

Chemical Name	Boc-Leu-OH.H2O
Synonyms	Boc-L-Leucine.H2O; Boc-L-Leu-OH; Boc-L-Leucine Monohydrate
CAS Number	13139-15-6
CAT Number	RF-PI115
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C11H21NO4
Molecular Weight	231.29
Density	1.061±0.06 g/cm3
Boiling Point	356℃ at 760 mmHg
Brand	Ruifu Chemical

Item	Specifications
Appearance	White or Off-White Crystalline Powder
Specific Rotation	-23.0° ~ -26.0° (C=1, AcOH)
Purity / Analysis Method	≥98.0% (HPLC)
Melting Point	82.0 ~ 90.0℃
Test Standard	Enterprise Standard
Usage	Pharmaceutical Intermediates; Organic Synthesis

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. Commercial Supply Carfilzomib (CAS: 868540-17-4) Related Intermediates:
Boc-L-Leucine.H2O;Boc-L-Leucine monohydrate; CAS: 13139-15-6
Boc-L-Homophenylalanine; Boc-L-HomePhe-OH; CAS: 100564-78-1
2-Bromopropene CAS: 557-93-7

Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent.The mechanism of action of carfilzomib is as a Proteasome Inhibitor, Carfilzomib irreversibly binds to and inhibits the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome, a protease complex responsible for degrading a large variety of cellular proteins. Inhibition of proteasome-mediated proteolysis results in an accumulation of polyubiquinated proteins, which may lead to cell cycle arrest, induction of apoptosis, and inhibition of tumor growth.
Carfilzomib is used in treatment of refractory multiple myeloma. Carfilzomib is associated with a low rate of serum enzyme elevations during treatment and has been implicated to rare instances of clinically apparent, acute liver injury some of which have been fatal.
Carfilzomib is a second-generation, irreversible, peptide epoxyketone class proteasome inhibitor that targets the chymotrypsin-like β5 subunit of the constitutive 20S proteasome (IC50 = 5.2 nM) and the β5i subunit of the immunoproteasome 20Si (LMP7; IC50 = 14 nM) with minimal cross reactivity to other proteases. It can induce cell cycle arrest and apoptosis in human cancer cell lines including multiple myeloma, lymphoma, and various solid tumors

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We are also focusing on improving the stuff management and QC system so that we could keep great advantage in the fiercely-competitive business for 8 Year Exporter ECPPA - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu , The product will supply to all over the world, such as: Oslo, San Diego, Denver, Our product quality is one of the major concerns and has been produced to meet the customer's standards. "Customer services and relationship" is another important area which we understand good communication and relationships with our customers is the most significant power to run it as a long term business.