Benzyl Bromide CAS 100-39-0 Purity >99.0% (GC) Factory

Benzyl Bromide (CAS: 100-39-0) is an aromatic compound in which the benzene ring substituted with a bromomethyl group, and is produced by the reaction of toluene with bromine in the presence of an oxidizing agent.  It is a combustible, colorless to yellowish liquid. Insoluble in water and easily soluble in most organic solvents. Has a strong tearing effect and unpleasant pungent odor, minimum irritant concentration of 4 mg/m3, intolerable concentration of 50-60 mg/m3. Benzyl Bromide is widely useful in organic synthesis as a benzyl protecting group for alcohols and carboxylic acids. It is used in the preparation of foaming and frothing agents, quaternary ammonium compounds, peniclins, photographic chemicals, synthetic resins, dyes and plasticizers and esters. Benzyl Bromide is an aromatic halide that is mainly used as a protecting agent for protecting hydroxy group of alcohols via O-benzylation reaction.

Benzyl Bromide is synthesized by toluene bromination. Toluene heated to 50℃, add bromine reaction, the reaction temperature of 75-80℃, reaction 6h, fractional distillation at atmospheric pressure to remove the fraction before 140℃, and then distillation under reduced pressure, collect 112-114℃(2.0kPa) fraction, to get benzyl bromide. 

Hazard Toxic by inhalation and by skin absorption. A lachrymator.  Corrosive to metals and tissue. Health Hazard Inhalation causes irritation of nose and throat; severe exposure may cause pulmonary edema. Vapors cause severe eye irritation; liquid can burn eyes. Skin contact causes irritation. Ingestion causes irritation of mouth and stomach. Incompatibilities May form explosive mixture with air. Contact with water forms hydrogen bromide and benzyl alcohol. Incompatible with strong oxidizers, bases, magnesium. Attacks metals, except nickel and lead, in the presence of moisture.