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Big discounting Methyl 2-Hydroxy-3-Methoxy-3 3-Diphenylpropanoate - 3-Benzyl-6-Bromo-2-Chloroquinoline CAS 654655-68-2 Bedaquiline Fumarate Intermediate Purity ≥99.0% (HPLC) Factory – Ruifu Featured Image
  • Big discounting Methyl 2-Hydroxy-3-Methoxy-3 3-Diphenylpropanoate - 3-Benzyl-6-Bromo-2-Chloroquinoline CAS 654655-68-2 Bedaquiline Fumarate Intermediate Purity ≥99.0% (HPLC) Factory – Ruifu

Big discounting Methyl 2-Hydroxy-3-Methoxy-3 3-Diphenylpropanoate - 3-Benzyl-6-Bromo-2-Chloroquinoline CAS 654655-68-2 Bedaquiline Fumarate Intermediate Purity ≥99.0% (HPLC) Factory – Ruifu

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Big discounting Methyl 2-Hydroxy-3-Methoxy-3 3-Diphenylpropanoate - 3-Benzyl-6-Bromo-2-Chloroquinoline CAS 654655-68-2 Bedaquiline Fumarate Intermediate Purity ≥99.0% (HPLC) Factory – Ruifu Detail:

Commercial Supply Bedaquiline Related Intermediates:
3-Benzyl-6-Bbromo-2-Mmethoxyquinoline CAS: 654655-69-3
3-Benzyl-6-Bromo-2-Chloroquinoline CAS: 654655-68-2
3-(Dimethylamino)-1-(Naphthalen-1-yl)propan-1-one Hydrochloride CAS: 5409-58-5  
Bedaquiline Fumarate CAS: 845533-86-0

Chemical Name 3-Benzyl-6-Bromo-2-Chloroquinoline
Synonyms 6-Bromo-2-Chloro-3-(Phenylmethyl)quinoline; Bedaquiline Impurity B; Bedaquiline Fumarate Impurity 5
CAS Number 654655-68-2 
CAT Number RF-PI107
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C₁₆H₁₁BrClN
Molecular Weight 332.62
Brand Ruifu Chemical
Item Specifications
Appearance White to Off-White or Light Yellow Powder
Purity / Analysis Method ≥99.0% (HPLC)
Melting Point 100.0~120.0℃
Moisture (K.F) ≤0.50%
Residue on ignition ≤0.50%
Total Impurities ≤1.00%
Test Standard Enterprise Standard
Usage Intermediate of Bedaquiline Fumarate (CAS: 845533-86-0)

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3-Benzyl-6-bromo-2-chloroquinoline (CAS: 654655-68-2) is a main intermediate of Bedaquiline Fumarate (CAS: 845533-86-0). Bedaquiline Fumarate is a diarylquinone drug developed by Janssen Pharmaceutical. The drug, which was approved in 2012 for the treatment of multidrug-resistant tuberculosis (MDR-TB), was developed in partnership with Johnson & Johnson and represents the first new tuberculosis therapy approved in over four decades. Bedaquiline Fumarate used in combination therapy for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of th mycobacteria.

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Big discounting Methyl 2-Hydroxy-3-Methoxy-3 3-Diphenylpropanoate - 3-Benzyl-6-Bromo-2-Chloroquinoline CAS 654655-68-2 Bedaquiline Fumarate Intermediate Purity ≥99.0% (HPLC) Factory – Ruifu detail pictures

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    5 Stars By Olivia from Mexico - 2018.11.06 10:04
    Factory equipment is advanced in the industry and the product is fine workmanship, moreover the price is very cheap, value for money!
    5 Stars By Athena from El Salvador - 2018.11.22 12:28
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