Bottom price Cholestyramine - Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API High Quality – Ruifu

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We thinks what prospects think, the urgency of urgency to act from the interests of a client position of theory, allowing for greater high-quality, reduced processing costs, rates are much more reasonable, won the new and previous consumers the support and affirmation for Formula Weight 319.38, Sodium Methanesulfinate, Molecular Formula C20H20O9, Through more than 8 years of business, we have accumulated rich experience and advanced technologies in the production of our products.

Bottom price Cholestyramine - Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API High Quality – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6

Name	Sorafenib
Synonyms	Sorafenib Free Base
CAS Number	284461-73-0
CAT Number	RF-API04
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C21H16ClF3N4O3
Molecular Weight	464.82
Brand	Ruifu Chemical

Item	Specifications
Appearance	White to Off-White Powder
Purity / Analysis Method	≥99.0% (HPLC)
Identification	H-NMR, MS
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Single Impurity	≤0.2% (HPLC)
Total Impurities	≤1.0% (HPLC)
Test Standard	Enterprise Standard
Usage	Sorafenib Tosylate (CAS: 475207-59-1)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Sorafenib Tosylate (CAS: 475207-59-1) is a new type of multi-target antitumor drug, was developed by the German Bayer Pharmaceuticals, and displayed expansive antitumor activity in preclinical animal tests. Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and HCC. Sorafenib Tosylate (CAS: 475207-59-1) can simultaneously affect tumor cells and tumor blood vessels. It has a double antitumor effect: it can block the cell signal transduction pathways mediated by RAF/MEK/ERK to directly inhibit tumor cell growth, while also inhibiting VEGF and platelet derived growth factors (PDGF) receptors to prevent the formation of new tumor blood vessels, thus indirectly inhibiting tumor cell growth. Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.

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