4-Cyclopropylnaphthalen-1-Amine Hydrochloride CAS 1533519-92-4 Lesinurad Intermediate Purity >99.0% (HPLC)

Short Description:

4-Cyclopropylnaphthalen-1-Amine Hydrochloride

Synonyms: Lesinurad Intermediate 3 

CAS: 1533519-92-4

Purity: >99.0% (HPLC)

Appearance: Off-White to Light Yellow Powder

Intermediate of Lesinurad (CAS: 878672-00-5)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 4-Cyclopropylnaphthalen-1-Amine Hydrochloride (CAS: 1533519-92-4) with high quality, intermediate of Lesinurad (CAS: 878672-00-5). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Lesinurad Intermediates, Please contact: alvin@ruifuchem.com

Lesinurad Intermediates:

Chemical Properties:

Chemical Name 4-Cyclopropylnaphthalen-1-Amine Hydrochloride 
Synonyms Lesinurad Intermediate 3; 4-Cyclopropylnaphthalen-1-Amine HCl; 4-Cyclopropyl-1-Naphthalenamine Hydrochloride; 4-Cyclopropyl-1-Naphthalenamine HCl; Lesinurad Impurity 14 HCl
Stock Status In Stock, Commercial Production
CAS Number 1533519-92-4
Molecular Formula C13H14ClN
Molecular Weight 219.71 g/mol
COA & MSDS Available
Origin Shanghai, China
Category   Intermediate of Lesinurad (CAS: 878672-00-5) 
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance Off-White to Light Yellow Powder
Off-White Powder 
Loss on Drying <0.50% 0.2% 
Purity / Analysis Method >99.0% (HPLC)  99.3% 
Total Impurities <1.00% 0.7%
1 H NMR Spectrum Consistent with Structure Complies 
LCMS Consistent with Structure Complies 
Conclusion The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

4-Cyclopropylnaphthalen-1-Amine Hydrochloride (CAS: 1533519-92-4) is used as an intermediate in the synthesis of Lesinurad (CAS: 878672-00-5). Approved by the FDA late in 2015, Lesinurad is an urate anion exchange transporter 1 (URAT1) inhibitor for use in the treatment of gout. Ardea Biosciences, which is a subsidiary of AstraZeneca, developed Lesinurad to be used in a combination therapy with xanthine oxidase inhibitors for the treatment of hyperuricaemia associated with gout. The approval process is ongoing in several other countries across the globe, with the EMA Committee for Medicinal Products for Human Use giving Lesinurad a positive opinion for use as an adjunctive therapy in combination with xanthine oxidase inhibitors to treat hyperuricaemia.

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