N-Propyl-Sulfamide Sodium Salt CAS 1642873-03-7 Macitentan Intermediate Purity >99.0% (HPLC-ELSD)

Short Description:

Chemical Name: N-Propyl-Sulfamide Sodium Salt 

CAS: 1642873-03-7

Purity: >99.0% (HPLC-ELSD)

Appearance: White Powder

Intermediate of Macitentan (CAS: 441798-33-0)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Product Detail

Related Products

Product Tags

Macitentan Related Intermediates:

1642873-03-7 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Propyl-Sulfamide Sodium Salt (CAS: 1642873-03-7) with high quality, intermediate of Macitentan (CAS: 441798-33-0). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Macitentan intermediates, Please contact: alvin@ruifuchem.com

1642873-03-7 - Chemical Properties:

Chemical Name N-Propyl-Sulfamide Sodium Salt 
Synonyms N-Propylsulfamide Sodium Salt; N-Propylsulfuric Diamide-Sodium; Macitentan Intermediate 2
Stock Status In Stock, Commercial Production  
CAS Number 1642873-03-7
Molecular Formula C3H11N2NaO2S
Molecular Weight 162.18 g/mol
Storage Temp.  Inert Atmosphere, Room Temperature
COA & MSDS Available
Place of Origin   Shanghai, China
Product Categories     Pharmaceutical Intermediates 
Brand Ruifu Chemical

1642873-03-7 - Specifications:

Items Specifications  Results
Appearance White Powder  White Powder  
Water by Karl Fischer  <1.00% 0.56% 
Purity (HPLC-ELSD)  >99.0%  99.7%
Assay (Titration) >99.0%  99.9%
Infrared Spectrum Consistent with Structure Complies 
NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Macitentan (CAS: 441798-33-0)

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

1642873-03-7 - Application:

N-Propyl-Sulfamide Sodium Salt (CAS: 1642873-03-7) is used as an intermediate of Macitentan (CAS: 441798-33-0). Macitentan is an anchiral sulfadiazine derivative. In vitro studies have shown that it is an orally active endothelin ETA and ETB receptor antagonists can block endothelin-induced vasoconstriction in trachea and aorta. Developed by Swiss Actelion Pharmaceuticals Company and approved by FDA on October 18, 2013, it was first listed in the United States. It is mainly used for the treatment of pulmonary hypertension (PAH). Its trade name is Opsumit. Compared with other drugs for the treatment of PAH, marcetitan plays a role mainly by slowing down the disease progression and can significantly reduce the morbidity and mortality of patients with PAH.

  • Write your message here and send it to us