Vildagliptin CAS 274901-16-5 Assay 98.0%~102.0% API High Quality
Shanghai Ruifu Chemical Co., Ltd. is the leading supplier of Vildagliptin (CAS: 274901-16-5) with high quality, used in the treatment of Type 2 Diabetes Mellitus (T2DM).
Ruifu Chemical has been supplying pharmaceutical intermediates and API (active pharmaceutical ingredient) more than 15 years, can provide worldwide delivery, competitive price, excellent service.
Purchase Vildagliptin, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | Vildagliptin |
| Synonyms | LAF-237; NVP-LAF 237; Galvus |
| CAS Number | 274901-16-5 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C17H25N3O2 |
| Molecular Weight | 303.4 |
| Melting Point | 148.0℃~152.0℃ |
| Density | 1.27 |
| Solubility | Soluble in DMSO and Water |
| Shelf Life | 24 Months When Properly Stored |
| COA & MSDS | Available |
| Storage Conditions | 2-8℃ Refrigerator |
| Shipping Conditions | Ambient |
| Origin of Product | Shanghai, China |
| Product Categories | API (Active Pharmaceutical Ingredient) |
| Brand | Ruifu Chemical |
| Test Items | Specifications | Results |
| Characteristics | ||
| Appearance | White or off-white crystalline powder | White crystalline powder |
| Solubility | Freely soluble in water, sparing soluble in butanone, practically insoluble in MTBE. | Complies |
| Melting Point | 148.0~152.0℃ | 149.5~150.5℃ |
| Specific Optical Rotation | -100.0° ~ -104.0° | -102.2° |
| Identification | ||
| HPLC | The retention time of the main peak of the test solution corresponds to that of the reference substance | Complies |
| IR | It should be consistent with the infrared spectrum of the reference substance | Complies |
| Alkalinity | 9.0~11.0 | 10.0 |
| Appearance of Solution | Clear and colorless; any opalescene produced is not more pronounced than that of reference suspension I; any color produced is not more intensely colored than that of yellow reference solution I. | Complies |
| Chloride ( Cl) | ≤0.01% | <0.01% |
| Sulfate (SO4) | ≤0.02% | <0.02% |
| Loss on Drying | ≤0.50% | 0.04% |
| Residue on Ignition | ≤0.10% | 0.08% |
| Relate Substances | ||
| MX20003 | ≤0.10% | 0.023% |
| MX20005 | ≤0.10% | Not detected |
| MX20006 | ≤0.10% | Not detected |
| MX20002 | ≤0.10% | 0.014% |
| MX20004 | ≤0.10% | Not detected |
| MX20007 | ≤0.10% | 0.037% |
| MX200074 | ≤0.10% | Not detected |
| Any Individual Unspecified Impurity | ≤0.10% | 0.023% |
| Total Impurities | ≤0.50% | 0.097% |
| Isomer | ≤0.10% | 0.004% |
| 3-Amino-1-Adamantanol | ≤0.10% | 0.030% |
| Residual Solvents | ||
| Methanol | ≤0.30% | Not detected |
| Isobutanol | ≤0.50% | Not detected |
| Ethyl Acetate | ≤0.50% | Not detected |
| Isopropanol | ≤0.50% | Not detected |
| Butanone | ≤0.50% | 0.035% |
| MTBE | ≤0.50% | Not detected |
| Acetonitrile | ≤0.041% | Not detected |
| Toluene | ≤0.089% | Not detected |
| Benzene | ≤0.0002% | Not detected |
| Heavy Metals (as Pb) | ≤20ppm | <20ppm |
| Assay | 98.0%~102.0% (Calculated on dried basis) | 100.6% |
| Conclusion: The product has been tested and complies with the given specifications | ||
Package: Fluorinated bottle, aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2-8℃) and well-ventilated warehouse away from incompatible substances. Prevent direct sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes
R28 - Very Toxic if swallowed
R38 - Irritating to the skin
R41 - Risk of serious damage to eyes
R48 - Danger of serious damage to health by prolonged exposure
Safety Description
S24/25 - Avoid contact with skin and eyes.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs 3077
HS Code 2933990099
Vildagliptin (CAS: 274901-16-5), developed by Novartis Pharmaceutical Co., Ltd, is another oral administrated inhibitor of Dipeptidyl peptidase-IV after Sitagliptin. In 2008, it is approved for marketing in the European Union for the treatment of type 2 diabetes. Diabetes is a chronic metabolic disease with its prevalence being increased year by year. Type 2 diabetes is a complicated diseases caused with the combined action between polygenic genetic factors and environmental factors.
