China Factory for 2-Phenylethylamine - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu
China Factory for 2-Phenylethylamine - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu Detail:
Manufacturer with High Purity and Stable Quality
Supply Irinotecan and Related Intermediates:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Chemical Name | 7-Ethyl-10-Hydroxycamptothecin |
Synonyms | SN-38 |
CAS Number | 86639-52-3 |
CAT Number | RF-PI242 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C22H20N2O5 |
Molecular Weight | 392.41 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Light Yellowish White Crystals Powder |
Identification (IR, UV) | (1) Ultraviolet ray absorption spectrum accord with the demands (2) Infrared ray absorption spectrum concordant with reference standard spectrum shall comply with approved tests |
Melting Point | 228.0~235.0℃ |
Related Substances | ≤1.5% |
10-Hydroxycamptothecin | ≤0.30% |
7-Cthylcamptothecin | ≤0.70% |
Maximum Unknown Impurity | ≤0.50% |
Loss on Drying | ≤1.0% |
Heavy Metals | ≤10ppm |
Residue on Ignition | ≤0.10% |
Clarity of Solution | Clear |
Assay | ≥98.0% (HPLC) |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediate of Irinotecan |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) with high quality. 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. 7-Ethyl-10-Hydroxycamptothecin (SN-38), is the active metabolite of Irinotecan, a semisynthetic derivative of camptothecin, a quinoline-based alkaloid found in the bark of the Chinese camptotheca tree and the Asian nothapodytes tree. Although 7-Ethyl-10-Hydroxycamptothecin is up to 1,000 times more potent than Irinotecan, it has not been converted into a viable drug candidate because it is insoluble. It is presently being subjected to clinical trials in combination with other moieties which may ultimately allow it to be efficacious as an antineoplastic drug.
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We will constantly satisfy our respected customers with our good excellent, superior value and superior assistance due to we're additional experienced and far more hard-working and do it in cost-effective way for China Factory for 2-Phenylethylamine - 7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity – Ruifu , The product will supply to all over the world, such as: Victoria, Vietnam, Zambia, We have more than 8 years of experience in this industry and have a good reputation in this field. Our products have won praise from customers worldwide. Our aim is to help customers realize their goals. We are making great efforts to achieve this win-win situation and sincerely welcome you to join us.
By Marcia from Singapore - 2017.09.28 18:29
Hope that the company could stick to the enterprise spirit of "Quality, Efficiency, Innovation and Integrity", it will be better and better in the future.
By Danny from Turkmenistan - 2018.09.12 17:18