China New Product Irinotecan HCl Trihydrate - Canagliflozin Hemihydrate CAS 928672-86-0 Purity ≥99.0% (HPLC) T2DM API High Purity – Ruifu

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China New Product Irinotecan HCl Trihydrate - Canagliflozin Hemihydrate CAS 928672-86-0 Purity ≥99.0% (HPLC) T2DM API High Purity – Ruifu Detail:

Chemical Name	Canagliflozin Hemihydrate
CAS Number	928672-86-0
CAT Number	RF-API22
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C24H27FO6S
Molecular Weight	462.53
Brand	Ruifu Chemical

Item	Specifications
Appearance	White Powder
Identification	HPLC/NMR
Solubility	Very Soluble in methanol; Soluble in ethanol, acetonitrile; Slightly soluble in water
Purity / Analysis Method	≥99.0% (HPLC)
Individual Impurity	≤0.10%
Total Impurities	≤0.50%
Residual Solvents
Methanol	≤3000ppm
Ethanol	≤5000ppm
Acetonitrile	≤400ppm
Dichloromethane	≤600ppm
Ethyl Acetate	≤5000ppm
THF	≤720ppm
Toluene	≤890ppm
Test Standard	Chinese Pharmacopoeia (CP); Enterprise Standard
Usage	Active Pharmaceutical Ingredient (API); SGLT-2 inhibitors Type 2 Diabetes

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Canagliflozin is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors (SGLT2) used for the treatment of type 2 diabetes. It was developed by Mitsubishi Tanabe Pharma and is marketed under license by Janssen, a division of Johnson & Johnson. Canagliflozin is responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter causes blood glucose to be eliminated through the urine. In March 2013, canagliflozin became the first SGLT2 inhibitor to be approved in the United States.

Canagliflozin, to mention the advantage, this drug helps patients to reduce blood sugars without increasing the likelihood of gaining weight as long as a healthy, balanced diet is followed and regular exercise taken. In addition, Canagliflozin has a broad prospect due to its significant antiobesity effects and few hypoglycemic events.

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