Chinese Professional N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine - Sorafenib Tosylate CAS 475207-59-1 Purity ≥99.0% (HPLC) API High Quality – Ruifu
Chinese Professional N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine - Sorafenib Tosylate CAS 475207-59-1 Purity ≥99.0% (HPLC) API High Quality – Ruifu Detail:
Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
Chemical Name | Sorafenib Tosylate |
CAS Number | 475207-59-1 |
CAT Number | RF-API05 |
Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
Molecular Formula | C28H24ClF3N4O6S |
Molecular Weight | 637.03 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Light Yellow or White Powder |
Purity / Analysis Method | ≥99.0% (HPLC) |
Melting Point | 225.0~235.0℃ |
Heavy Metals | ≤10ppm |
Loss on Drying | ≤0.5% |
Test Standard | Enterprise Standard |
Usage | Sorafenib Tosylate (CAS: 475207-59-1) in the treatment of RCC & HCC |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
Sorafenib Tosylate (CAS: 475207-59-1) is a new type of multi-target antitumor drug, was developed by the German Bayer Pharmaceuticals, and displayed expansive antitumor activity in preclinical animal tests. Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and HCC. Sorafenib Tosylate (CAS: 475207-59-1) can simultaneously affect tumor cells and tumor blood vessels. It has a double antitumor effect: it can block the cell signal transduction pathways mediated by RAF/MEK/ERK to directly inhibit tumor cell growth, while also inhibiting VEGF and platelet derived growth factors (PDGF) receptors to prevent the formation of new tumor blood vessels, thus indirectly inhibiting tumor cell growth. Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.
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We emphasize development and introduce new products into the market every year for Chinese Professional N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine - Sorafenib Tosylate CAS 475207-59-1 Purity ≥99.0% (HPLC) API High Quality – Ruifu , The product will supply to all over the world, such as: Austria, Bandung, Ethiopia, Many goods fully conform to the most rigorous of international guidelines and with our first-rate delivery service you will have them delivered at any time and in any place. And because Kayo deals in the entire spectrum of protective equipment, our customers don't have to waste time shopping around.
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The customer service staff's attitude is very sincere and the reply is timely and very detailed, this is very helpful for our deal,thank you.
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