Cholestyramine CAS 11041-12-6 USP API Factory High Purity

Short Description:

Chemical Name: Cholestyramine 

CAS: 11041-12-6

Appearance: White or Off-White Powder, Odorless or Has a Slightly Amine-like Odor, Hygroscopic

Purity: Each g exchanges 2.0~2.4g of Sodium Taurocholate 

In the treatment of type Ⅱa hyperlipoproteinemia

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


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Description:

Supply with High Purity and Stable Quality
Chemical Name: Cholestyramine 
CAS: 11041-12-6 
Cholestyramine in the treatment of type Ⅱa hyperlipoproteinemia
API High Quality, Commercial Production

Chemical Properties:

Chemical Name Cholestyramine
Synonyms Cholestyramine Resin; Colestyramine
CAS Number 11041-12-6
CAT Number RF-API23
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C27H47N
Molecular Weight 385.66878
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White or Off-White Powder, Odorless or has a slightly amine-like odor, Hygroscopic
Identification The infrared absorption spectrum of the sample should be consistent with the reference standard
pH 4.0~6.0
Dialyzable Quaternary Amine Should meet the requirements
Chloride 13.0%~17.0% (Calculated on the dried basis)
Loss on Drying ≤12.0%
Residue on Ignition ≤0.10%
Heavy Metals ≤20ppm
Bacterial Count ≤1000 cfu/g
Yeast and Mold ≤100 cfu/g
Escherichia Coli Should not be detected
Live Mite Test Should not be detected
Purity Calculated on the dried basis, each g exchanges 2.0g~2.4g of Sodium Taurocholate
Test Standard United States Pharmacopeia (USP)
Usage Active Pharmaceutical Ingredient (API)

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

1

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Cholestyramine (CAS: 11041-12-6) with high quality, active pharmaceutical ingredient (API). Cholestyramine (Colestyramine) is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol. A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion.

Cholestyramine: it is mainly used for the treatment of type Ⅱa hyperlipoproteinemia, especially in familial hypercholesterolemia. Also it is used for the treatment of primary biliary cirrhosis, drug-induced cholestatic jaundice itching, hypercholesterolemia, chronic cholecystitis, gallstones, Porphyrin thesaurismosis. Treatment of Atherosclerosis: 4~5g, 3 times/d. Itching: Start amount of 6~10g/d, maintenance dose of 3g/d, administration for 3 times. Long-term use can reduce intestinal binding bile salt, and cause fat malabsorption, long-term use should add vitamin A, D, K and other fat-soluble vitamins and calcium appropriately, gastrointestinal responders may be appropriate with stomach medication.

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