Methyl-β-Cyclodextrin CAS 128446-36-6 (Me-β-CD)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Methyl-β-Cyclodextrin (Me-β-CD) (CAS: 128446-36-6) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Methyl-β-Cyclodextrin, Please contact: alvin@ruifuchem.com
| Chemical Name | Methyl-β-Cyclodextrin |
| Synonyms | MβCD; Me-β-CD; Methyl-β-CD; Methyl-beta-Cyclodextrin; beta-Cyclodextrin Methyl Ethers |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 128446-36-6 |
| Molecular Formula | C54H94O35 |
| Molecular Weight | 1303.3 g/mol |
| Melting Point | 180.0~182.0℃(lit.) |
| Density | 1.4±0.1 g/cm3 |
| Water Solubility | Soluble in Water, Almost Transparency |
| COA & MSDS | Available |
| Shelf Life | 36 Months if Stored Properly |
| Category | Pharmaceutical Excipients |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White Powder, Odorless, Insipid Innocent, Sweet | Conforms |
| Specific Rotation [a]20/D | +154.0° to +165.0° (C=1 in H2O) | +156.2° |
| pH | 5.0~7.5 | 6.90 |
| Clarity & Color of Solution | Clear, Colorlesss Without Foreign Substances | Conforms |
| The Average Substitution | 11.2~13.3 | 13.03 |
| Moisture Content | ≤5.00% | 3.9% |
| Residue on Ignition | ≤0.50% | 0.39% |
| Heavy Metals | ≤0.0025% | <0.0025% |
| Sulfide | ≤0.20% | <0.05% |
| Chloride | ≤0.20% | <0.05% |
| Arsenic Salt | ≤0.0005% | <0.0002% |
| Reducing Sugars | ≤0.20% | <0.20% |
| Light-Absorbing Impurities | ≤0.10 (230 nm~350 nm) ≤0.05 (350 nm~750 nm) | Conforms |
| Alpha Cyclodextrin | ≤0.25% | Conforms |
| Gamma Cyclodextrin | ≤0.25% | Conforms |
| Other Related Substances | ≤0.50% | Conforms |
| Microbiological Test | ||
| Total Aerobic Microbial Counts | ≤1000cfu/g | ≤10cfu/g |
| Total Molds & Yeasts Counts | ≤100cfu/g | ≤10cfu/g |
| Escherichia Coli | Not Detectable | None |
| Salmonella | Absent | Absent |
| Pathogenic Bacteria | Not Detectable | None |
| Methoxy Content | 10.4~31.2% | Conforms |
| Infrared Spectrum | Conforms to Structure | Conforms |
| Conclusion | The product has been tested and complies with the given specifications | |
| Application | Pharmaceutical Excipients, Food Additives, Cosmetics etc. | |
Package: Bottle, Aluminium foil bag, 10kg/25kg/Cardboard Drum, or according to customer's requirement.
Storage: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from strong light, heat and moisture. Incompatible with heat, oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 3505100000 |
Methyl-β-Cyclodextrin (Me-β-CD) (CAS: 128446-36-6), is a macrocyclic compound that can form inclusion complexes with a number of guest molecules. It shows higher solubility in aqueous solutions and greater solubilizing and complexing power compared to the parent β-cyclodextrin. MβCD can be used to enhance the enzyme activity and enantioselectivity of subtilizing enzyme in organic solvents.
Methyl-β-Cyclodextrin (Me-β-CD) (CAS: 128446-36-6), among common cyclodextrin derivatives, methylated cyclodextrins have greater surface tension. Pharmaceutical excipients, food additives, cosmetics industry.
In food manufacturing, Methyl-β-Cyclodextrin is mainly used to eliminate peculiar smell, improve the stability of flavor and pigment, and enhance emulsification and moisture resistance in food manufacturing. Improving the taste of food is a good stabilizer and flavoring agent for the pharmaceutical, food and cosmetics manufacturing industries. In medicine, the solubility and bioavailability of drugs can be improved, the efficacy of drugs can be increased or the dosage can be reduced, the release rate of drugs can be adjusted or controlled, the side effects of drugs can be reduced, and the stability of drugs can be enhanced. Especially more effective for aqueous solutions of oil-soluble molecules. Increase the solubility of non-polar substances, such as fatty acids, lipids, vitamins and cholesterol, used in cell culture. Used in food, cosmetics, pesticides, daily chemical products, textile dyeing and finishing, printing, and ink. It has good viscosity reduction effect in coating thickener.
Methyl-β-Cyclodextrin is a randomly methylated form of the cyclic oligosaccharide β-Cyclodextrin. Methyl-β-Cyclodextrin contains seven D-(+)-glucopyranose units that contain randomized hydrogen or methyl groups. Methyl-β-Cyclodextrin has been used to improve the aqueous solubility of various compounds and to extract cholesterol from lipid membranes.
Methyl-β-Cyclodextrin is a cholesterol-removing agent mainly used for lipid raft disruption. It may also be used for detergent removal from protein-lipid-detergent ternary mixture to produce 2D membrane protein crystals due to its high solubility and affinity for detergents generally used in membrane protein chemistry.
Methyl-β-Cyclodextrin (Me-β-CD) (CAS: 128446-36-6), is a cholesterol remover, mainly used to destroy lipid raft. Methyl-β-Cyclodextrin can induce caspase-dependent apoptosis in PEL cells and inhibit the growth and infection of PEL cells without obvious adverse effects, showing potential effective anti-tumor activity.
Methyl-β-Cyclodextrin (Me-β-CD) (CAS: 128446-36-6) has strong water and oil solubility, as the stromal molecule to include the complexes and to be used in including of drugs spices etc.
Me-β-CD can change the original natures of materials, in medical field, it can promote the dissolusion efficiency of the drugs, enhancing bioavailability and solubility of drugs, so that to reduce the doseut increase the efficacy.
Me-β-CD can adjust and controls the releasing of drugs, to enhance the stability. It can changes mmucosa sbsorption in drugs, specially for the oil soluble molecules it can be more effective to increase the water solubility.
Function and Application of Methyl-β-Cyclodextrin (Me-β-CD) (CAS: 128446-36-6)
1. Methyl-β-Cyclodextrin is a cholesterol-removing agent mainly used for lipid raft disruption. It may also be used for detergent removal from protein-lipid-detergent ternary mixture to produce 2D membrane protein crystals due to its high solubility and affinity for detergents generally used in membrane protein chemistry.
2. Methyl-β-Cyclodextrin is used in food, cosmetics, pesticides, daily chemical products, textile dyeing and finishing, printing and ink. Very good viscosity reduction in paint thickeners
3. Increases the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture.
Methyl-β-Cyclodextrin Application
Methyl-β-Cyclodextrin is mainly used to eliminate odor, improve the stability of flavor and pigment, enhance emulsification ability and moisture-proof ability in food manufacturing.
Methyl-β-Cyclodextrin used as stabilizer in food and cosmetics industry.
Methyl-β-Cyclodextrin has good viscosity reduction effect in coating thickener.
1. In medicine, Methyl-β-Cyclodextrin can improve the solubility and bioavailability of drugs, increase the efficacy of drugs or reduce the dosage of drugs, adjust or control the release rate of drugs, reduce the toxic and side effects of drugs, and enhance the stability of drugs.
2. In the field of food and spices, Methyl-β-Cyclodextrin can improve the stability and long-term performance of nutrition molecules, and cover up or correct the bad smell and taste of food nutrition molecules.
3. In the field of cosmetics, Methyl-β-Cyclodextrin can reduce the stimulation of model molecules in cosmetics to skin mucosal tissues, enhance the stability of substances, and prevent the volatilization and oxidation of nutrients.
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