Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Factory High Quality

Short Description:

Chemical Name: Dantrolene Sodium Salt Hydrate 

CAS: 14663-23-1

Appearance: Yellowish-Orange to Orange Crystalline Powder

Skeletal Muscle Relaxant. Calcium Channel Inhibitor

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


Product Detail

Related Products

Product Tags

Description:

Supply with High Purity and Stable Quality
Chemical Name: Dantrolene Sodium Salt Hydrate 
CAS: 14663-23-1 
Skeletal Muscle Relaxant. Calcium Channel Inhibitor
API High Quality, Commercial Production

Chemical Properties:

Chemical Name Dantrolene Sodium Salt Hydrate
Synonyms 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Salt Hydrate
CAS Number 14663-23-1
CAT Number RF-API78
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C14H11N4NaO5
Molecular Weight 338.25
Solubility Soluble in DMSO 
Shipping Condition Shipped Under Ambient Temperature
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Yellowish-Orange to Orange Crystalline Powder. No visible evidence of contamination by foreign matter
Identification A The IR Absorption (197K)
Identification B The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay
Identification C Meets the requirements of the flame test for Sodium (191)
Identification D Part 1: A voluminous, white, crystalline precipitate is formed
Part 2: The precipitate does not disappear
Part 3: The precipitate dissolves completely
Part 4: No precipitate is formed
Water Content (by K.F) 14.5%~17.0% 
Particle Size 90% less than 200um
Assay 90.0%~96.0% of C14H10N405 on the anhydrous basis
Related Substances (HPLC, Area%)
Related Compound A ≤0.15%
Related Compound B ≤0.50%
Related Compound C ≤0.30%
Residual Solvents  
Ethanol ≤2000ppm
Methanol ≤2000ppm
Acetone ≤2000ppm
DMF ≤620ppm
Heavy Metals ≤10ppm
Shelf Life 2 Years
Test Standard United States Pharmacopoeia (USP)
Usage Skeletal Muscle Relaxant. Calcium Channel Inhibitor

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

1

FAQ:

Application:

Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), is a small molecule inhibitor of Ryanodine receptor antagonist and a Calcium channel inhibitor. Dantrolene Sodium Salt is a skeletal muscle relaxant, which inhibits intracellular Ca 2+release from the sarcoplasmic reticulum. Blockade of Ca2+ release from the sarcoendoplasmic reticulum, strongly related to excitation and contraction of muscles, generates a muscle relaxant effect correlated with Dantrolene. The neurotoxicity presented by pronounced glutamate activity is correlated to excessive rises in cytoplasmic Ca2+ levels, and Dantrolene is accordingly indicated as a neuroprotective agent against neurotrasmitter-induced excitotoxicity. Dantrolene, Sodium Salt is an inhibitor of RyR-1 and RyR-3.

  • Write your message here and send it to us