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factory customized Tribenzoate - 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate – Ruifu Featured Image
  • factory customized Tribenzoate - 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate – Ruifu

factory customized Tribenzoate - 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate – Ruifu

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In order to give you convenience and enlarge our business, we also have inspectors in QC Team and assure you our best service and product for CAS 557-93-7, 210.54, Weight 614.75, We welcome buyers all around the word to make contact with us for foreseeable future small business associations. Our products and solutions are the most beneficial. Once Selected, Perfect Forever!
factory customized Tribenzoate - 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate – Ruifu Detail:

Manufacturer Supply High Quality, Commercial Production
Chemical Name: 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
CAS: 160129-45-3

Chemical Name 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
Synonyms 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; 7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS Number 160129-45-3
CAT Number RF-PI395
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C10H10ClNO
Molecular Weight 195.65
Melting Point 103.0 to 107.0℃
Solubility Soluble in Methanol
Brand Ruifu Chemical
Item Specifications
Appearance Light Green to Light Yellow Powder
Identification Methods NMR, HPLC
Purity / Analysis Method ≥99.0% (HPLC)
Loss on Drying ≤1.0%
Residue on Ignition ≤0.50%
Any Single Impurity ≤0.50%
Total Impurities ≤1.0%
Test Standard Enterprise Standard
Usage Intermediate of Tolvaptan (CAS 150683-30-0), treatment of Hyponatremia

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

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7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one (CAS 160129-45-3) is an intermediate in the synthesis of Tolvaptan (CAS 150683-30-0). Tolvaptan is a selective, competitive orally active nonpeptide arginine vasopressin V2 receptor antagonist with an IC50 of 1.28µM for the inhibition of AVP-induced platelet aggregation. Tolvaptan is used to treat hyponatremia associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone. Tolvaptan is also in fast-track clinical trials for polycystic kidney disease. Treatment with Tolvaptan causes rapid and sustained body weight reductions concurrent with increases in urine output, improves and/or normalizes serum sodium in hyponatremic patients, reduces signs and symptoms of congestion and increases thirst.

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factory customized Tribenzoate - 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate – Ruifu detail pictures

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