Factory source Azelastine - Eflornithine Hydrochloride Monohydrate CAS 96020-91-6 High Purity – Ruifu

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Factory source Azelastine - Eflornithine Hydrochloride Monohydrate CAS 96020-91-6 High Purity – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Chemical Name: Eflornithine Hydrochloride Monohydrate
CAS: 96020-91-6
Used in the treatment of Hirsutism
API High Quality, Commercial Production

Chemical Name	Eflornithine Hydrochloride Monohydrate
Synonyms	Eflornithine HCl hydrate; DFMO; DL-α-Difluoromethylornithine Hydrochloride Monohydrate
CAS Number	96020-91-6
CAT Number	RF-API53
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C6H12F2N2O2·HCl·H2O
Molecular Weight	236.65
Brand	Ruifu Chemical

Item	Specifications
Appearance	White or Almost White Crystalline Powder
Water	≤9.0%
Residue on Ignition	≤0.10%
Heavy Metals	≤10ppm
Assay	98.0%~102.0% (Titration) (on dry basis)
Purity	≥98.0% (HPLC)
Test Standard	Enterprise Standard
Usage	Active Pharmaceutical Ingredient (API)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Eflornithine hydrochloride hydrate is irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism. Eflornithine hydrochloride is a specific, irreversible inhibitor of ornithine decarboxylase. Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks’ treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.

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