Factory source Methyl Isobutyrylacetate - Tenofovir CAS 147127-20-6 API Anti-HIV High Quality – Ruifu

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Factory source Methyl Isobutyrylacetate - Tenofovir CAS 147127-20-6 API Anti-HIV High Quality – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Commercial Supply Tenofovir Related Intermediates
Tenofovir Disoproxil Fumarate CAS: 202138-50-9
Tenofovir CAS: 147127-20-6
(R)-Propylene Carbonate CAS: 16606-55-6
Adenine CAS: 73-24-5

Name Tenofovir
Synonyms (R)-PMPA; (R)-9-(2-Phosphonomethoxypropyl)Adenine
CAS Number 147127-20-6
CAT Number RF-API07
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C9H14N5O4P
Molecular Weight 287.22
Brand Ruifu Chemical
Item Specifications
Appearance White or Almost White Crystalline Powder
Assay / Analysis Method 98.0%~102.0% (on anhydrous basis)
Solubility Slightly Soluble in Water (0.1g in 100ml); Practically Insoluble in Methanol(0.01g in 100ml and over)
Sulphate Ash ≤1.5%
Moisture (K.F) ≤5.0%
Specification Optical Rotation -19.0° ~ -23.0° (at 25℃ anhydrous basis)
PMPA Monoester Impurity ≤1.5% (HPLC)
Any Single Max Impurity ≤0.5% (HPLC)
Total Impurities ≤3.0% (HPLC)
Enantiomeric Purity ≤0.5% (HPLC)
9-propenyl adenine (HPLC) ≤75ppm

 

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. Tenofovir disoproxil (Viread) is the first nucleotide analogue approved by the American FDA to treat HIV-1 infections. Tenofovir disoproxil is a drug used in the AIDS cocktail treatment method, and research shows that it has the ability to increase monkeys’ immunity to immunodeficiency viruses (similar to the human AIDS virus). Tenofovir disoproxil is used in combination with other reverse transcriptase inhibitors to treat HIV-1 infections and hepatitis B. Tenofovir is a drug used for the treatment of chronic heptatitis B as well as prevention and treatment of HIV/AIDS. It is a kind of nucleotide analog, acting as the reverse-transcriptase inhibitor (NtRTI). It inhibits the activity of HIV reverse transcriptase through competing with the natural substrate deoxyadenosine 5’-triphosphate, causing the termination of DNA chain.


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We usually think and practice corresponding for the change of circumstance, and grow up. We aim at the achievement of a richer mind and body as well as the living for Factory source Methyl Isobutyrylacetate - Tenofovir CAS 147127-20-6 API Anti-HIV High Quality – Ruifu , The product will supply to all over the world, such as: The Swiss, Lithuania, Senegal, Many years of work experience, we have realized the importance of providing good quality products and the best before-sales and after-sales services. Most problems between suppliers and clients are due to poor communication. Culturally, suppliers can be reluctant to question things they do not understand. We break down those barriers to ensure you get what you want to the level you expect, when you want it. faster delivery time and the product you want is our Criterion .
  • The accounts manager made a detailed introduction about the product, so that we have a comprehensive understanding of the product, and ultimately we decided to cooperate.
    5 Stars By Freda from India - 2017.06.25 12:48
    We have been engaged in this industry for many years, we appreciate the work attitude and production capacity of the company, this is a reputable and professional manufacturer.
    5 Stars By Letitia from Argentina - 2017.01.11 17:15
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