Fixed Competitive Price Revaprazan HCL49 - Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality – Ruifu

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Fixed Competitive Price Revaprazan HCL49 - Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality – Ruifu Detail:

Supply Vonoprazan Fumarate and Related Intermediate
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2

Chemical Name Vonoprazan Fumarate
Synonyms TAK-438
CAS Number 1260141-27-2; 881681-01-2
CAT Number RF-API99
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C21H20FN3O6S
Molecular Weight 461.463
Brand Ruifu Chemical
Item Specifications
Appearance White or Almost-White Crystalline Powder
Identification 1 H-NMR Consistent with the Standard
Identification IR The IR Absorption spectrum of the sample concordant with reference standard
Identification HPLC The retention time of the sample concordant with reference standard
Related Substances
Impurity A ≤0.20%
Impurity B ≤0.15%
Impurity C ≤0.15%
Any Other Impurity ≤0.10%
Total Impurities ≤1.0%
Residual Solvents
Methanol ≤0.30%
Ethanol ≤0.50%
Ethyl Acetate ≤0.50%
Assay / Analysis Method 98.0%~102.0% (By HPLC)
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.

1

Vonoprazan Fumurate (TAK-438) (CAS: 1260141-27-2; 881681-01-2), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate (Takecab), discovered and developed by Takeda and Otsuka, was approved by the PMDA of Japan in December 2014. Vonoprazan Fumarate is mainly used for the treatment of helicobacter pylori infection, gastroesophageal reflux, peptic ulcer, duodenal ulcer, esophagitis, gastric ulcer and other gastric acid related diseases. The product has a strong, lasting inhibition of gastric acid secretion. At the treatment dose, Vonoprazan Fumarate has little effect on other enzymes and little effect on physiological functions of the body. It is safe and more tolerable.


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Fixed Competitive Price Revaprazan HCL49 -  Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality – Ruifu detail pictures


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With reliable excellent approach, great name and ideal consumer services, the series of products and solutions produced by our company are exported to many countries and regions for Fixed Competitive Price Revaprazan HCL49 - Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality – Ruifu , The product will supply to all over the world, such as: United Kingdom, UK, Luxembourg, Based on our guiding principle of quality is the key to development, we continually strive to exceed our customers' expectations. As such, we sincerely invite all interested companies to contact us for future cooperation, We welcome old and new customers to hold hands together for exploring and developing; For more information, be sure to feel free to contact us. Thanks. Advanced equipment, strict quality control, customer-orientation service, initiative summary and improvement of defects and extensive industry experience enable us to guarantee more customer satisfaction and reputation which, in return, brings us more orders and benefits. If you are interested in any of our merchandise, make sure you feel free to contact us. Inquiry or visit to our company are warmly welcome. We sincerely hope to start a win-win and friendly partnership with you. You can see more details in our website.
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