Good Wholesale Vendors 5-AMP-Na2 - Pirfenidone CAS 53179-13-8 Purity ≥99.0% IPF – Ruifu

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Good Wholesale Vendors 5-AMP-Na2 - Pirfenidone CAS 53179-13-8 Purity ≥99.0% IPF – Ruifu Detail:

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Chemical Name: Pirfenidone
CAS: 53179-13-8

Chemical Name	Pirfenidone
Synonyms	Perfenidone; 5-Methyl-1-Phenylpyridine-2(1H)-one; PFD; S-7701; AMR-69
CAS Number	53179-13-8
CAT Number	RF-API108
Stock Status	In Stock
Molecular Formula	C12H11NO
Molecular Weight	185.22
Melting Point	96.0 to 97.0℃
Solubility	Soluble in DMSO
Brand	Ruifu Chemical

Item	Specifications
Appearance	White to Light Yellow Crystalline Powder
Identification	IR
Purity	≥99.0%
Loss on Drying	≤0.50%
Sulfated Ash	≤0.20%
Single Impurity	≤0.50%
Total Impurities	≤1.0%
Heavy Metals	≤20ppm
Test Standard	Enterprise Standard
Usage	API, Idiopathic Pulmonary Fibrosis (IPF)

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Pirfenidone (CAS: 53179-13-8) is in a group of medicines called antifibrotic agents. Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver. It affects your body’s immune system and reduces the amount of fibrosis (scarring) in the lungs. Pirfenidone is one of two medicines that are approved in Canada to treat Idiopathic Pulmonary Fibrosis (IPF). Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. It was first approved in Japan for the treatment of patients with idiopathic pulmonary fibrosis after clinical trials, under the trade name of Pirespa by Shionogi, in 2008. It was approved for use in the European Union in 2011, in Canada in 2012, and in the United States in October 2014.

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