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Good Wholesale Vendors Guanfacine Hydrochloride - Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Purity – Ruifu Featured Image
  • Good Wholesale Vendors Guanfacine Hydrochloride - Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Purity – Ruifu

Good Wholesale Vendors Guanfacine Hydrochloride - Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Purity – Ruifu

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Good Wholesale Vendors Guanfacine Hydrochloride - Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Purity – Ruifu Detail:

Supply Temozolomide and Related Intermediates:
Temozolomide CAS: 85622-93-1
4(5)-Amino-5(4)-Imidazolecarboxamide CAS: 360-97-4
5(4)-Amino-4(5)-Imidazolecarboxamide Hydrochloride CAS: 72-40-2

Chemical Name Temozolomide
Synonyms 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-Carboxamide
CAS Number 85622-93-1
CAT Number RF-API29
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C6H6N6O2
Molecular Weight 194.15
Melting Point 212℃ dec.
Brand Ruifu Chemical
Item Specifications
Appearance White to Light Pink Powder
Identification  By IR, HPLC
Residual Solvents Dimethyl Sulphoxide ≤0.50%
Related Substances
Impurity AIC ≤0.10%
Single Impurity ≤0.10%
Rest Unknown Impurities ≤0.30%
Total Impurities ≤0.30%
Heavy Metals ≤10ppm
Loss on Drying ≤0.50%
Residue on Ignition ≤0.10%
Assay 99.0%~101.0% (HPLC on the dried basis)
Test Standard Enterprise Standard
Usage Active Pharmaceutical Ingredient (API)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Temozolomide (CAS: 85622-93-1) with high quality. Temozolomide (TMZ) is an oral alkylating agent used to treat Glioblastoma Multiforme (GBM) and Astrocytomas, Metastatic Melanoma. 

Temozolomide is the first effective orally-taken imidazole and tetrazine-class anticancer drug which belongs to the second generation of an alkylating agent with antitumor activity without liver metabolic activation after oral administration. It is characterized by easily penetration through the blood-brain barrier, good tolerance and being not superimposed with other drugs toxicity, and having synergistic effect with radiotherapy which is suitable for treating malignant glioma recurrence after conventional treatment such as glioblastoma multiforme tumors or degenerative astrocytoma. It is first-line drug for treatment of metastatic melanoma.

Temozolomide had been first synthesized by Cancer Research UK Group, and then be transferred to the Schering-Plough Company (United States) for development.  It has a novel chemical structure and belongs to a four-imidazole derivative. In 1999, it has been approved for enter into market in EU and the US wherein the permitted indication in United States is mainly for second-line treatment of glioblastoma multiforme and degenerative star gliomas and approved indications of EU is for treating developing or relapsing glioblastoma multiforme which has already been subject to conventional therapy. The efficacy of temozolomide on treating glioblastoma multiforme has received more recognition in Europe.

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Each individual member from our large performance revenue crew values customers' needs and company communication for Good Wholesale Vendors Guanfacine Hydrochloride - Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Purity – Ruifu , The product will supply to all over the world, such as: Egypt, Poland, Senegal, We are proud to supply our products to every auto fan all around the world with our flexible, fast efficient services and strictest quality control standard which has always approved and praised by customers.
    • The customer service reprersentative explained very detailed, service attitude is very good, reply is very timely and comprehensive, a happy communication! We hope to have a opportunity to cooperate.
    5 Stars By Ann from Turkmenistan - 2018.07.12 12:19
    We have been appreciated the Chinese manufacturing, this time also did not let us disappoint,good job!
    5 Stars By Rigoberto Boler from Uzbekistan - 2017.08.21 14:13
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