High Performance CPT-11 Trihydrate - Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API High Quality – Ruifu
High Performance CPT-11 Trihydrate - Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API High Quality – Ruifu Detail:
Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
Name | Sorafenib |
Synonyms | Sorafenib Free Base |
CAS Number | 284461-73-0 |
CAT Number | RF-API04 |
Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
Molecular Formula | C21H16ClF3N4O3 |
Molecular Weight | 464.82 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White to Off-White Powder |
Purity / Analysis Method | ≥99.0% (HPLC) |
Identification | H-NMR, MS |
Loss on Drying | ≤1.0% |
Residue on Ignition | ≤0.1% |
Single Impurity | ≤0.2% (HPLC) |
Total Impurities | ≤1.0% (HPLC) |
Test Standard | Enterprise Standard |
Usage | Sorafenib Tosylate (CAS: 475207-59-1) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Manufacturer with High Purity and Stable Quality
Commercial Supply Sorafenib Tosylate (CAS: 475207-59-1) Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methyl-2-Pyridinecarboxamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
Sorafenib Tosylate (CAS: 475207-59-1) is a new type of multi-target antitumor drug, was developed by the German Bayer Pharmaceuticals, and displayed expansive antitumor activity in preclinical animal tests. Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and HCC. Sorafenib Tosylate (CAS: 475207-59-1) can simultaneously affect tumor cells and tumor blood vessels. It has a double antitumor effect: it can block the cell signal transduction pathways mediated by RAF/MEK/ERK to directly inhibit tumor cell growth, while also inhibiting VEGF and platelet derived growth factors (PDGF) receptors to prevent the formation of new tumor blood vessels, thus indirectly inhibiting tumor cell growth. Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.
Product detail pictures:
Related Product Guide:
We believe that long term partnership is a result of high quality, value added service, rich experience and personal contact for High Performance CPT-11 Trihydrate - Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API High Quality – Ruifu , The product will supply to all over the world, such as: South Korea, Israel, Austria, Our items are exported worldwide. Our customers are always satisfied with our reliable quality, customer-oriented services and competitive prices. Our mission is "to continue to earn your loyalty by dedicating our efforts to the constant improvement of our merchandise and services in order to ensure the satisfaction of our end-users, customers, employees, suppliers and the worldwide communities in which we cooperate".
By Henry from Zambia - 2017.11.01 17:04
Production management mechanism is completed, quality is guaranteed, high credibility and service let the cooperation is easy, perfect!
By Merry from Seychelles - 2017.08.18 11:04