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High Quality Benzoyl - 3-Amino-1-Adamantanol CAS 702-82-9 Vildagliptin Intermediate – Ruifu Featured Image
  • High Quality Benzoyl - 3-Amino-1-Adamantanol CAS 702-82-9 Vildagliptin Intermediate – Ruifu

High Quality Benzoyl - 3-Amino-1-Adamantanol CAS 702-82-9 Vildagliptin Intermediate – Ruifu

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High Quality Benzoyl - 3-Amino-1-Adamantanol CAS 702-82-9 Vildagliptin Intermediate – Ruifu Detail:

Manufacturer with High Purity and Competitive Price
Supply Vildagliptin and Related Intermediates:
Vildagliptin CAS: 274901-16-5
3-Amino-1-hydroxyadamantane CAS: 702-82-9
L-Prolinamide CAS: 7531-52-4
Boc-L-Proline CAS: 15761-39-4
(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile CAS: 207557-35-5

Chemical Name 3-Amino-1-Adamantanol 
Synonyms 1-Amino-3-Hydroxyadamantane; 3-Amino-1-Hydroxyadamantane
CAS Number 702-82-9
CAT Number RF-PI102
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C10H17NO
Molecular Weight 167.25
Brand Ruifu Chemical
Item Specifications
Appearance White Crystalline Powder
Purity / Analysis Method ≥98.5% (HPLC) (dry basis)
Moisture (K.F) ≤0.50%
Residue on Ignition ≤0.50%
Melting Point 266.5℃~272.5℃
Test Standard Enterprise Standard
Usage Intermediate of Vildagliptin (CAS: 274901-16-5)

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 3-Amino-1-adamantanol (CAS: 702-82-9) with high quality. Vildagliptin is synthesised from 3-Amino-1-adamantanol.

Vildagliptin is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas. Vildagliptin has been shown to reduce hyperglycemia in type 2 diabetes mellitus. Novartis has since withdrawn its intent to submit vildagliptin to the FDA, as of July 2008. It was approved in Feb 2008 by European Medicines Agency for use within the EU and is listed on the Australian PBS with certain restrictions.

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