High Quality for Acetaminophen - Deslorelin Acetate CAS 57773-65-6 GnRH Agonist High Quality – Ruifu

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High Quality for Acetaminophen - Deslorelin Acetate CAS 57773-65-6 GnRH Agonist High Quality – Ruifu Detail:

Manufacturer Commercial Supply with High Purity and Stable Quality
Chemical Name: Deslorelin Acetate
Sequences: Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt
CAS: 57773-65-6 
API High Quality, Commercial Production

Chemical Name Deslorelin Acetate
Sequences Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt
CAS Number 57773-65-6
CAT Number RF-API16
Stock Status In Stock, Production Scale Up to Kilograms
Molecular Formula C64H83N17O12
Molecular Weight 1282.48
Brand Ruifu Chemical
Item Specifications
Appearance White Powder or Almost White Powder
Identity by HPLC The retention is same with the reference substance
Amino Acid Composition Glu: 0.85~1.10
Pro: 0.85~1.10
Leu: 0.90~1.10
Tyr: 0.85~1.10
His: 0.85~1.10
Arg: 0.85~1.10
Ser: Present
Trp: Present
Purity (By HPLC) ≥98.0% (By Area Integration)
Related Substance(By HPLC) Total Impurities ≤2.0%
Largest Single Impurity ≤1.0%
Acetate Content (By HPLC) ≤12.0%
Water Content (Karl Fischer) ≤8.0%
Peptide Content (N%) ≥80.0%
Bacterial Endotoxins ≤70 IU/mg
Residual Organic Solvents Acetonitrile ≤0.041% (By GC)
DMF ≤0.088% (By GC)
MEOH ≤0.3% (By GC)
TFA ≤0.1% (By HPLC)
Assay 95%~105% (By Anhydrous, Acetic Acid-free)
Test Standard Enterprise Standard
Origin of Product Synthetic
Storage Conditions -20°C Freezer. Keep Package Close When Not In Use.
Shipping Requirements Ice Bags, Desiccant Bags
Attention Only for Research, Not for Human Use
Usage Active Pharmaceutical Ingredient (API)

Package: Bottle, Vials, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Deslorelin acetate is a gonadotropin releasing hormone super-agonist.  In is used in veterinary medicine to induce ovulation and to stabilize high-risk pregnancies. Deslorelin is a synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone super-agonist (GnRH agonist) with potential antineoplastic activity. It binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. It stops the production of sex hormones. It is currently used to induce ovulation in mares as part of the artificial insemination process. It is also used to stabilize high-risk pregnancies, mainly of livestock and is also used to treat benign prostate hyperplasia in dogs. It is manufactured by Thorne BioScience LLC and was introduced to the USA market following the withdrawal of Ovuplant. It has been listed. D’eslorelin is being studied in the treatment of cancer as a way to block sex hormones made by the ovaries or testicles. It belongs to the family of drugs called gonad-releasing hormone analogs. It is used for the induction of ovulation in mares. D’eslorelin binds to and activates pituitary gona releasing hormone (GnRH) receptors. Continuous, prolonged administration of gose in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and  (LH), leading to a significant decline in test production; in females, prolonged administration results in a decrease in estradiol production.


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