High Quality (R)-(-)-Mandelic Acid - Ethyl 4-Chloro-3-Hydroxybutanoate CAS 10488-69-4 Assay ≥98.0% (GC) High Purity – Ruifu

Manufacturer Supply with High Purity and Stable Quality
Ethyl 4-Chloro-3-Hydroxybutanoate CAS 10488-69-4
Ethyl (S)-4-Chloro-3-Hydroxybutyrate CAS 86728-85-0
Ethyl (R)-(+)-4-Chloro-3-Hydroxybutyrate CAS 90866-33-4
Chiral Compounds, High Quality, Commercial Production

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Ethyl 4-Chloro-3-Hydroxybutanoate (CAS: 10488-69-4) with high quality, widely used in organic synthesis, synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API) synthesis.

Shanghai Ruifu Chemical Co., Ltd. plays an important role in the chiral chemistry, the company is committed to the production of chiral compounds. Our products are widely praised by customers.

Ethyl 4-Chloro-3-Hydroxybutanoate (CAS: 10488-69-4) is a key chiral intermediate in statins. For example, Ethyl 4-chloro-3-hydroxybutyrate is an intermediate of Olacetam, Olacetam in the treatment of alzheimer’s disease.

Ethyl 4-Chloro-3-Hydroxybutanoate (CAS: 10488-69-4), it is an important organic intermediate to synthesize precursor compounds of cholesterol-lowering drugs, but also for many activities synthesis of drugs such as hydroxymethylglutaryl reductase inhibitors and 1,4-dihydropyridine β-blockers. It has the advantage of being easy to synthesize and inexpensive, and it is a very cost-effective way to prepare Ethyll-4-Chloro-3-Hydroxy Butyrate by asymmetric reduction as a reaction raw material. Moreover, during the reaction, the microorganism does not use the product of the reaction to produce other new impurities, so that the preparation reaction can be carried out by using whole cells of the microorganism, and the reaction method is simpler. At present, there have been many reports on the preparation of chiral Ethyll-4-Chloro-3-Hydroxy Butyrate by asymmetric reduction of ethyl 4-chloroacetoacetate. The main preparation methods are chemical methods and biological methods. Among them, microbial catalysis in biological methods is a hot spot of research. Microbial catalysis utilizes the stereoselectivity of a specific microbial cell-specific enzyme system to selectively convert a substrate into a product in a cell. However, due to the complexity of the enzyme system present in the cell, the optical purity of the catalytic product is not high, and it is necessary to screen an excellent microbial strain or to improve by cloning a recombinant gene. Coenzyme addition is also required to provide the reducing power of the reaction.