High Quality (S)-(+)-3-Hydroxytetrahydrofuran - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu
High Quality (S)-(+)-3-Hydroxytetrahydrofuran - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu Detail:
Manufacturer Supply; High Purity and Competitive Price
Shanghai Ruifu Chemical Co., Ltd. Commercial Supply Carfilzomib (CAS: 868540-17-4) Related Intermediates:
Boc-L-Leucine.H2O;Boc-L-Leucine monohydrate; CAS: 13139-15-6
Boc-L-Homophenylalanine; Boc-L-HomePhe-OH; CAS: 100564-78-1
2-Bromopropene CAS: 557-93-7
Chemical Name | Boc-Leu-OH.H2O |
Synonyms | Boc-L-Leucine.H2O; Boc-L-Leu-OH; Boc-L-Leucine Monohydrate |
CAS Number | 13139-15-6 |
CAT Number | RF-PI115 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C11H21NO4 |
Molecular Weight | 231.29 |
Density | 1.061±0.06 g/cm3 |
Boiling Point | 356℃ at 760 mmHg |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White or Off-White Crystalline Powder |
Specific Rotation | -23.0° ~ -26.0° (C=1, AcOH) |
Purity / Analysis Method | ≥98.0% (HPLC) |
Melting Point | 82.0 ~ 90.0℃ |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediates; Organic Synthesis |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. Commercial Supply Carfilzomib (CAS: 868540-17-4) Related Intermediates:
Boc-L-Leucine.H2O;Boc-L-Leucine monohydrate; CAS: 13139-15-6
Boc-L-Homophenylalanine; Boc-L-HomePhe-OH; CAS: 100564-78-1
2-Bromopropene CAS: 557-93-7
Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent.The mechanism of action of carfilzomib is as a Proteasome Inhibitor, Carfilzomib irreversibly binds to and inhibits the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome, a protease complex responsible for degrading a large variety of cellular proteins. Inhibition of proteasome-mediated proteolysis results in an accumulation of polyubiquinated proteins, which may lead to cell cycle arrest, induction of apoptosis, and inhibition of tumor growth.
Carfilzomib is used in treatment of refractory multiple myeloma. Carfilzomib is associated with a low rate of serum enzyme elevations during treatment and has been implicated to rare instances of clinically apparent, acute liver injury some of which have been fatal.
Carfilzomib is a second-generation, irreversible, peptide epoxyketone class proteasome inhibitor that targets the chymotrypsin-like β5 subunit of the constitutive 20S proteasome (IC50 = 5.2 nM) and the β5i subunit of the immunoproteasome 20Si (LMP7; IC50 = 14 nM) with minimal cross reactivity to other proteases. It can induce cell cycle arrest and apoptosis in human cancer cell lines including multiple myeloma, lymphoma, and various solid tumors
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We strive for excellence, service the customers", hopes to become the best cooperation team and dominator enterprise for personnel, suppliers and customers, realizes value share and continuous promotion for High Quality (S)-(+)-3-Hydroxytetrahydrofuran - Boc-Leu-OH.H2O CAS 13139-15-6 Purity ≥98.5% (HPLC) – Ruifu , The product will supply to all over the world, such as: Kenya, Sri Lanka, Brazil, We follow up the career and aspiration of our elder generation, and we're eager to open up a new prospect in this field, We insist on "Integrity, Profession, Win-win Cooperation", because we have now a strong backup, that are excellent partners with advanced manufacturing lines, abundant technical strength, standard inspection system and good production capacity.
By Nora from Singapore - 2018.12.28 15:18
The goods are very perfect and the company sales manager is warmful, we will come to this company to purchase next time.
By Marguerite from Birmingham - 2018.06.26 19:27