High reputation R-Mandelic Acid - (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Atazanavir Intermediate High Purity – Ruifu

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High reputation R-Mandelic Acid - (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Atazanavir Intermediate High Purity – Ruifu Detail:

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Chemical Name	(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane
Synonyms	(2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane; (2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane; Darunavir Intermediate
CAS Number	98737-29-2
CAT Number	RF-PI286
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C15H21NO3
Molecular Weight	263.33
Solubility	Insoluble in Water. Soluble in Methanol, Chloroform
Shipping Condition	Shipped Under Ambient Temperature
Brand	Ruifu Chemical

Item	Specifications
Appearance	White to Off-White Crystalline Powder
Identification (HPLC)	The Identification is Confirmed by HPLC
Melting Point	123.0~128.0℃
Moisture (K.F)	≤0.50%
Residue on Ignition	≤0.20%
Purity / Analysis Method	≥98.0% (HPLC)
Chlorohydrin (HPLC)	≤0.20%
Chloromethyl Ketone	≤0.10%
Other Single Impurity	≤0.20%
Total Impurities	≤1.0%
Chiral Impurity	≤0.30%
Test Standard	Enterprise Standard
Usage	Intermediate of Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS: 98737-29-2) with high quality.(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS: 98737-29-2) is an intermediate typically in the synthesis of Darunavir (CAS 206361-99-1).

Darunavir (CAS 206361-99-1) is a new kind of non peptide anti retroviral protease inhibitors in AIDS therapy. It is first developed by the Johnson pharmaceutical Iceland branch, Tibotec. It is of the highest bioavailability in the 6 protease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir and ABT378/r). It acts by blocking the formation of new and mature virus particles from the surface of the infected host cells and inhibiting the virus’s protease. When the product is used for a long time, it usually can reduce the HIV virus vector in blood, increase the count of CD4 cells, reduce the chance of HIV infection, improve the quality of life and prolong life. It is suitable for adults who are infected with the HIV virus but have no effect on the use of existing antiretroviral drugs. The drug must be combined with the use of low doses of ritonavir or other antiretroviral agents, in order to improve the efficacy.

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