HONB CAS 21715-90-2 N-Hydroxy-5-Norbornene-2,3-Dicarboximide Purity >99.0% (HPLC) Coupling Reagent

Short Description:

N-Hydroxy-5-Norbornene-2,3-Dicarboximide

Synonyms: HONB 

CAS: 21715-90-2

Purity: >99.0% (HPLC)

White to Off-White Crystalline Powder

Coupling Reagents, High Quality 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Hydroxy-5-Norbornene-2,3-Dicarboximide (HONB) (CAS: 21715-90-2) with high quality. Ruifu Chemical supplys a series of protecting reagents and coupling reagents. Ruifu can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase HONB, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name N-Hydroxy-5-Norbornene-2,3-Dicarboximide 
Synonyms HONB; N-Hydroxy-5-Norbornene-2.3-Dicarboxylic imide; N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-Dicarboxylic Acid imide; N-Hydroxy-5-Norbornene-2,3-Dicarboxylic acid imide; 2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
Stock Status In Stock, Mass Production
CAS Number 21715-90-2
Molecular Formula C9H9NO3
Molecular Weight 179.18 g/mol
Melting Point 164.0~170.0℃(lit.) 
Density 1.574 
Solubility in Water  Almost Transparency  
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Category   Coupling Reagents 
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White to Off-White Crystalline Powder  Complies      
Melting Point 164.0~170.0℃ 164.0~166.0℃
Water by Karl Fischer  <0.50% 0.26%
Sulfate <1.00% 0.7%
Chloride <0.10% 0.08%
Purity / Analysis Method >98.0% (HPLC)  99.1% 
Infrared Spectrum Conforms to Structure Complies      
1 H NMR Spectrum  Conforms to Structure Complies      
Solubility in EtOH Clear, 50mg/ml Pass
Conclusion The product has been tested & complies with the given specifications

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

21715-90-2 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes
36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany 3
TSCA Yes

Application:

N-Hydroxy-5-Norbornene-2,3-Dicarboximide (HONB) (CAS: 21715-90-2) is used in solution-phase peptide synthesis. Used in the synthesis of enkephalin analogs. HONB has been reported that its effect is better than N-Hydroxysuccinimide (HOSu,NHS). In peptide synthesis, it is an effective reagent for connecting with DCC. HONB decreases racemization in peptide synthesis and inhibits formation of N-acylureas. Generation, and obtain a high-yield peptide; the corresponding chloroformate can be used to introduce different types of amino protecting groups.

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