Hot New Products 6-Bromo-2-methoxy-3-benzylquinoline - Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 COVID-19 – Ruifu

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Hot New Products 6-Bromo-2-methoxy-3-benzylquinoline - Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 COVID-19 – Ruifu Detail:

Manufacturer with High Purity and Stable Quality
Commercial Supply Remdesivir and Related Intermediates

Chemical Name (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)tetrahydrofuran-2-Carbonitrile
Synonyms GS-441524; Remdesivir Metabolite; Remdesivir Intermediate; Nucleosid of Remdesivir; EVO984; Remdesivir O-Desphosphate Analogue; Remdesivir Related Compound 6 Impurity
CAS Number 1191237-69-0
CAT Number RF-PI298
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C12H13N5O4
Molecular Weight 291.26
Solubility Solubled in DMSO
Storag Cool Dry Place
Shipping Condition Shipped Under Ambient Temperature
Brand Ruifu Chemical
Item Specifications
Appearance White to Almost White Powder
Purity ≥99.0%
Alpha-Isomer ≤0.30%
O-Bn Derivative ≤0.30%
N-Bn Derivative ≤0.30%
Maximum Single Impurity ≤0.30%
Loss on Drying ≤1.0%
Residue on Ignition ≤0.50%
Heavy Metals ≤20ppm
Arsenic ≤2ppm
Test Standard Enterprise Standard
Usage Intermediate of Remdesivir (CAS 1809249-37-3); COVID-19

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Remdesivir nucleoside analogue (GS-441524, CAS 1191237-69-0) is an essential building block to the synthesis of Remdesivir triphosphate (1355149-45-9) and Remdesivir (1809249-37-3). GS-441524 is a nucleoside analogue antiviral drug which was developed by Gilead Sciences. This phosphorus analog is mainly an active compound in the treatment of Ebola and COVID-19. It is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats.


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