Hot New Products CDPC - Sevelamer Carbonate CAS 845273-93-0 API High Purity – Ruifu

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Hot New Products CDPC - Sevelamer Carbonate CAS 845273-93-0 API High Purity – Ruifu Detail:

Manufacturer Supply with High Purity and Stable Quality
Chemical Name: Sevelamer Carbonate CAS: 845273-93-0
Appearance: White to Yellowish Powder
Binding of Phosphate: 3.0~7.0mmol/g
Sevelamer Carbonate is a polymeric amine that binds phosphate and is used to treat hyperphosphatemia in patients with chronic kidney disease
API High Quality, Commercial Production

Chemical Name	Sevelamer Carbonate
Synonyms	2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
CAS Number	845273-93-0
CAT Number	RF-API28
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	(C3H7N)m.(C3H5ClO)n.(CH2O3)x
Molecular Weight	211.64
Brand	Ruifu Chemical

Item	Specifications
Appearance	White to Yellowish Powder
Identification A	By IR, To match with working standard
Identification B	Should be positive reaction
Chloride	≤0.10%
Loss on Drying	≤10.0%
Residue on Ignition	≤0.20%
Heavy Metals	≤20ppm
Solubility Test	Should be to match with the standard
Binding of Phosphate	3.0~7.0mmol/g
Soluble Oligomer	≤0.20%
Test Standard	Enterprise Standard
Attention	Protect from the light and Store in a cool dry place(≤5℃), Best use within six months
Usage	Active Pharmaceutical Ingredient (API)

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Sevelamer carbonate is a polymeric amine that binds phosphate and is used to treat HYPERPHOSPHATEMIA in patients with kidney disease. Sevelamer carbonate is an anion exchange resin, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. While the counterions differ for the two salts, the polymer itself, the active moiety involved in phosphate binding, is the same. Sevelamer carbonate is known chemically as poly(allylamine-co-N,N’-diallyl-1,3diamino-2-hydroxypropane) carbonate salt. Sevelamer carbonate is hygroscopic, but insoluble in water. Sevelamer Carbonate, a non-absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-based phosphate binders.

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