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Hot sale Factory (S)-(-)-2-Chloropropionic Acid - (S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu Featured Image
  • Hot sale Factory (S)-(-)-2-Chloropropionic Acid - (S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu

Hot sale Factory (S)-(-)-2-Chloropropionic Acid - (S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu

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Hot sale Factory (S)-(-)-2-Chloropropionic Acid - (S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu Detail:

Manufacturer with High Quality and Competitive Price
Commercial Supply Palonosetron Hydrochloride and Related Intermediates:
1,2,3,4-Tetrahydro-Naphthoic Acid CAS: 1914-65-4
(S)-1,2,3,4-Tetrahydro-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Chemical Name (S)-3-Aminoquinuclidine Dihydrochloride
Synonyms (S)-(-)-3-Aminoquinuclidine 2 HCL 
CAS Number 119904-90-4
CAT Number RF-CC112
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C7H16Cl2N2
Molecular Weight 199.12
Solubility in Water Soluble
Brand Ruifu Chemical
Item Specifications
Appearance White to Light Yellow Crystalline Powder 
IR Absorption Spectra Consistent with the Reference
Chloride Reaction Positive Reaction
Purity ≥98.0%
Loss on Drying ≤0.50%
Specific Rotation [α]D20 -22.0°~ -26.0° (C=1, H2O)
Heavy Metals ≤20ppm
Storage 5-8℃ Airtightness
Test Standard Enterprise Standard
Usage Palonosetron Hydrochloride (CAS: 135729-62-3) Intermediates 

(S)-3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Synthetic Route

(S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-3-Aminoquinuclidine dihydrochloride (CAS: 2133-40-6) with high quality. It is a pharmaceutical intermediate typically in the synthesis of Palonosetron Hydrochloride (CAS: 135729-62-3).

Palonosetron Hydrochloride (CAS: 135729-62-3) is a drug to inhibit nausea and vomiting, which is a new type highly selective, high-affinity 5-HT3 receptor antagonist that can block the vomiting reflex center peripheral neurons presynaptic 5-HT. Receptor excitement directly affects the central nervous system in 5-HT. Impulse receptor excitement generated by the role of vagal afferent nerve after area, blocking the vagus nerve endings in the gut, preventing signals to 5-HT. Receptor trigger zone can reduce the incidence of nausea and vomiting. Central clinically for the treatment of acute severe emetogenic chemotherapy induced delayed nausea and vomiting. Because of its high curative effect, little side effect, long half-life (about 40 h), small dosage, and so on, it has attracted much attention. With 1,2,3,4-tetrahydro-1-naphthoic acid as the starting material, the split, amination, reduction, cyclization, salt of palonosetron hydrochloride granisetron. Clinical studies showed that palonosetron can be used safely with corticosteroids, analgesics, antiemetics, antispasmodics and anticholinergic drugsas the starting material, the split, amination, reduction, cyclization, salt of palonosetron hydrochloride granisetron. 

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Hot sale Factory (S)-(-)-2-Chloropropionic Acid - (S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu detail pictures

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Our company since its inception, constantly regards product or service high quality as business life, continually improve creation technology, make improvements to product high-quality and consistently strengthen business total high-quality management, in strict accordance together with the national standard ISO 9001:2000 for Hot sale Factory (S)-(-)-2-Chloropropionic Acid - (S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu , The product will supply to all over the world, such as: Bogota, Macedonia, Japan, Wide selection and fast delivery for you! Our philosophy: Good quality, great service, keep improving. We are looking forward that more and more oversea friends join in our family for further development near the future!
    • The company has rich resources, advanced machinery, experienced workers and excellent services, hope you keep improving and perfecting your products and service, wish you better!
    5 Stars By Eartha from Panama - 2017.10.23 10:29
    This supplier's raw material quality is stable and reliable, has always been in accordance with the requirements of our company to provide the goods that quality meet our requirements.
    5 Stars By Alan from Estonia - 2017.09.26 12:12
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