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Hot-selling Imatinib Mesylate - Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant – Ruifu Featured Image
  • Hot-selling Imatinib Mesylate - Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant – Ruifu

Hot-selling Imatinib Mesylate - Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant – Ruifu

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Hot-selling Imatinib Mesylate - Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant – Ruifu Detail:

Manufacturer Supply Argatroban Related Intermediates:
Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6

Chemical Name Argatroban
Synonyms Argatroban Anhydrous
CAS Number 74863-84-6
CAT Number RF-API67
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C23H36N6O5S
Molecular Weight 508.63
Melting Point 188.0~189.0℃ 
Boiling Point  801.3ºC at 760 mmHg
Density 1.47 g/cm3
Shipping Condition Shipped Under Ambient Temperature
Brand Ruifu Chemical
Item Specifications
Appearance White to Off-White Crystalline Powder
Identification HPLC The retention time of principle peak obtained from Test solution conform with that obtained from Standard solution, as test in Assay
Identification IR Conforms to the IR Spectrum of AG RS
Identification UV In the 259nm and 332nm wavelength place should have maximum absorption
Water 2.5-4.5%
Solution Color & Clarity Solution Should be Clear Colorles
Relate Substances
Impurity A + Impurity H ≤0.10%
Impurity B ≤0.10%
Impurity C + Impurity E ≤0.10%
Impurity D ≤0.10%
Impurity I ≤0.10%
Bach of Unspecified Impurity  ≤0.10%
Total Impurities ≤0.30%
Residual Solvents
Methanol ≤3000ppm
Ethanol ≤5000ppm
Dichloromethane ≤600ppm
Ethyl Acetate  ≤5000ppm
Enantiomer (HPLC) ≤0.10%
Isomer Ratio (HPLC) 30.0%-40.0%
Chloride ≤0.01%
Residue on Ignition ≤0.10%
Heavy Metals ≤10ppm
Bacterial Endotoxins <5EU/mg
Microbial Limit TAMC ≤1000 cfu/g
Assay 98.0%-102.0% (on anhydrous basis)
Test Standard Enterprise Standard
Usage API, Synthetic Antithrombotic Agent Anticoagulant

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Argatroban (CAS: 74863-84-6) with high quality, API.
Argatroban (CAS: 74863-84-6) is a new synthetic antithrombotic agent useful in maintenance anticoagulation them ischemic stroke and disseminated intravascular coagulation. It is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the Food and Drug Administration (FDA) for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during percutaneous coronary interventions in patients who have HIT or are at risk for developing it. In 2012, it was approved by the MHRA in the UK for anticoagulation in patients with heparin-induced thrombocytopenia Type II (HIT) who require parenteral antithrombotic therapy.  

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