Indacaterol Maleate Intermediate CAS 312753-53-0 5,6-Diethyl-2,3-Dihydro-1H-Inden-2-Amine Hydrochloride

Short Description:

5,6-Diethyl-2,3-Dihydro-1H-Inden-2-Amine Hydrochloride

CAS: 312753-53-0

Appearance: White to Off-White Powder

Purity: >98.0% (HPLC) 

Intermediate of Indacaterol Maleate (CAS: 753498-25-8) in the treatment of COPD 

Contact: Dr. Alvin Huang 

Mobile/Wechat/WhatsApp: +86-15026746401 

E-Mail: alvin@ruifuchem.com 


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Intermediates of Indacaterol Maleate:

Chemical Properties:

Chemical Name 5,6-Diethyl-2,3-Dihydro-1H-Inden-2-Amine Hydrochloride 
Synonyms Indacaterol Maleate Intermediate; 5,6-Diethyl-2,3-Dihydro-1H-Inden-2-Amine HCl
CAS Number 312753-53-0
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C13H20ClN
Molecular Weight 225.76
Melting Point >250℃
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Item Specifications Specifications
Appearance White to Off-White Powder Conforms
Purity / Analysis Method >98.0% (HPLC) 99.37% (HPLC)
Loss on drying <0.50% 0.32%
Residue on Ignition <0.50%  0.11%
Individual Impurity <0.50% (HPLC) Conforms   
Total Impurities <1.00% (HPLC) 0.63%
Test Standard Enterprise Standard Conforms 
Usage Intermediate of Indacaterol Maleate (CAS: 753498-25-8) 

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

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312753-53-0 - Application:

Indacaterol Maleate (CAS: 753498-25-8) is a new, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist and bronchodilator. It is used in the treatment of chronic obstructive pulmonary disease (COPD) and asthma. The European Medicines Agency (EMA) approved indacaterol as a drug in 2009 under the Onbrez trade name while in the United States the Food and Drug Administration approved it under the trade name Arcapta in 2011. The drug is manufactured as its maleate salt form. Also, indacaterol is a chiral molecule; however, only the pure R-enantiomer is distributed. It needs to be taken only once a day, unlike competitors formoterol and salmeterol.  

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