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Lowest Price for AMP.2Na - (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu Featured Image
  • Lowest Price for AMP.2Na - (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu

Lowest Price for AMP.2Na - (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu

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We have probably the most state-of-the-art output equipment, experienced and qualified engineers and workers, recognized good quality manage systems plus a friendly skilled income workforce pre/after-sales support for Molecular Weight 104.1, Molecular Formula C5H10O3, Molecular Formula C18H26N2O2, We are looking forward to even greater cooperation with overseas customers based on mutual benefits. Please feel free to contact us for more detail!
Lowest Price for AMP.2Na - (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu Detail:

Manufacturer with High Quality and Competitive Price
Commercial Supply Palonosetron Hydrochloride and Related Intermediates:
1,2,3,4-Tetrahydro-Naphthoic Acid CAS: 1914-65-4
(S)-1,2,3,4-Tetrahydro-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Chemical Name (S)-1,2,3,4-Tetrahydro-Naphthoic Acid
Synonyms (1S)-1,2,3,4-Tetrahydronaphthalene-1-Carboxylic acid
CAS Number 85977-52-2
CAT Number RF-CC111
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C11H12O2
Molecular Weight 176.21
Melting Point 54.0~56.0℃ 
Brand Ruifu Chemical
Item Specifications
Appearance White or Almost White Crystalline Powder
Purity ≥99.0%
Enantimoer Excess e.e. ≥99.0%
Isomer Impurity ≤1.0%
Loss on Drying ≤0.50%
Relate Substance ≤1.0%
Moisture (K.F) ≤1.0%
Specific Rotation [α]D20 -59.0°~ -63.0°(C=0.3, Benzence)
Heavy Metals ≤20ppm
Storage 5-8℃ Airtightness
Test Standard Enterprise Standard
Usage Palonosetron Hydrochloride (CAS: 135729-62-3) Intermediates 

(S)-1,2,3,4-tetrahydro-naphthoic acid CAS: 85977-52-2 Route of Synthesis 

85977-52-2

Package: Bottle, Cardboard Drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-1,2,3,4-Tetrahydro-Naphthoic Acid (CAS: 85977-52-2) with high quality, used in synthesis of active pharmaceutical ingredient (API). It is an intermediate typically in the synthesis of Palonosetron Hydrochloride (CAS: 135729-62-3).

Palonosetron Hydrochloride (CAS: 135729-62-3) is a drug to inhibit nausea and vomiting, which is a new type highly selective, high-affinity 5-HT3 receptor antagonist that can block the vomiting reflex center peripheral neurons presynaptic 5-HT. Receptor excitement directly affects the central nervous system in 5-HT. Impulse receptor excitement generated by the role of vagal afferent nerve after area, blocking the vagus nerve endings in the gut, preventing signals to 5-HT. Receptor trigger zone can reduce the incidence of nausea and vomiting. Central clinically for the treatment of acute severe emetogenic chemotherapy induced delayed nausea and vomiting. Because of its high curative effect, little side effect, long half-life (about 40 h), small dosage, and so on, it has attracted much attention. With 1,2,3,4-tetrahydro-1-naphthoic acid as the starting material, the split, amination, reduction, cyclization, salt of palonosetron hydrochloride granisetron. Clinical studies showed that palonosetron can be used safely with corticosteroids, analgesics, antiemetics, antispasmodics and anticholinergic drugsas the starting material, the split, amination, reduction, cyclization, salt of palonosetron hydrochloride granisetron.  

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Lowest Price for AMP.2Na - (S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% e.e.≥99.0% Palonosetron Hydrochloride Intermediate – Ruifu detail pictures

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