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Manufactur standard Irinotecan Hydrochloride Intermediate - 2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory – Ruifu Featured Image
  • Manufactur standard Irinotecan Hydrochloride Intermediate - 2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory – Ruifu

Manufactur standard Irinotecan Hydrochloride Intermediate - 2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory – Ruifu

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Manufactur standard Irinotecan Hydrochloride Intermediate - 2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory – Ruifu Detail:

Manufacturer Supply, High Purity, Commercial Production
Chemical Name: 2-Chloroadenine
CAS: 1839-18-5

Chemical Name 2-Chloroadenine
Synonyms 6-Amino-2-Chloropurine; Cladribine EP Impurity B
CAS Number 1839-18-5
CAT Number RF-PI513
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C5H4ClN5
Molecular Weight 169.57
Brand Ruifu Chemical
Item Specifications
Appearance Yellowish to Off-White Powder
Assay / Analysis Method ≥98.0% (HPLC)
Melting Point ≥300℃
Loss on Drying ≤0.50%
Residue on Ignition ≤0.50%
Heavy Metals (as Pb) ≤0.001%
Total Impurities ≤2.0%
Test Standard Enterprise Standard
Usage Intermediate of Clofarabine (CAS: 123318-82-1), Cladribine (CAS: 4291-63-8)

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

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2-Chloroadenine (CAS: 1839-18-5) is mainly used as intermediate of Clofarabine (CAS: 123318-82-1), Cladribine (CAS: 4291-63-8) and other APIs. Clofarabine is a novel purine nucleoside anticancer drugs is first successfully developed by the Top10 biopharmaceutical company of the United States-Genzyme Corporation. On December 28, 2004 the US food and Drug Administration (FDA) used fast-track for approval of clofarabine for application to children with refractory or relapsed acute lymphocytic leukemia. Cladribine (2-chloro-2′-deoxyadenosine) is an adenosine deaminase-resistant analogue of deoxyadenosine. The drug has a broad range of in vitro activity against both lymphoid and myeloid neoplasms.

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